Skin tumors Rb(eing) uncovered
The Rb1 gene was the first bona fide tumor suppressor identified and cloned more than 25 years ago. Since then, a plethora of studies have revealed the functions of pRb and the existence of a sophisticated and strictly regulated pathway that modulates such functional roles. An emerging paradox affec...
Main Authors: | CLOTILDE eCOSTA, Jesus M Paramio, MIRENTXU eSANTOS |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-12-01
|
Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00307/full |
Similar Items
-
CELLULAR RESPONSES TO DNA DAMAGE AND ONCOGENESIS BY THE p53 AND pRb/E2F PATHWAYS
by: Elza Ibrahim Auerkari, et al.
Published: (2015-07-01) -
Aberrant Expression of Rb and pRb-780, pRb-795 in Lung Adenocarcinoma Patients with EGFR Mutations and Their Clinical Significance
by: Yunlong DONG, et al.
Published: (2017-05-01) -
Deregulated E2F Activity as a Cancer-Cell Specific Therapeutic Tool
by: Rinka Nakajima, et al.
Published: (2023-02-01) -
Simultaneous Analysis of the p16 Gene and Protein in Canine Lymphoma Cells and Their Correlation with pRb Phosphorylation
by: Leni Maylina, et al.
Published: (2022-07-01) -
Role of Retinoblastoma Protein Family (Rb/p105 and Rb2/p130) Expression in the Histopathological Classification of Borderline Ovarian Tumors
by: Valeria Masciullo, et al.
Published: (2020-11-01)