Cardiovascular Disease in Primary Sjögren’s Syndrome: Raising Clinicians’ Awareness
In the ever evolving landscape of systemic immune mediated diseases, an increased awareness regarding the associated cardiovascular system impairment has been noted in recent years. Even though primary Sjögren’s Syndrome (pSS) is one of the most frequent autoimmune diseases affecting middle-aged ind...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.865373/full |
| _version_ | 1817969101458374656 |
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| author | Mihnea Casian Mihnea Casian Ciprian Jurcut Alina Dima Ancuta Mihai Ancuta Mihai Silviu Stanciu Silviu Stanciu Ruxandra Jurcut Ruxandra Jurcut |
| author_facet | Mihnea Casian Mihnea Casian Ciprian Jurcut Alina Dima Ancuta Mihai Ancuta Mihai Silviu Stanciu Silviu Stanciu Ruxandra Jurcut Ruxandra Jurcut |
| author_sort | Mihnea Casian |
| collection | DOAJ |
| description | In the ever evolving landscape of systemic immune mediated diseases, an increased awareness regarding the associated cardiovascular system impairment has been noted in recent years. Even though primary Sjögren’s Syndrome (pSS) is one of the most frequent autoimmune diseases affecting middle-aged individuals, the cardiovascular profile of this specific population is far less studied, at least compared to other autoimmune diseases. Traditional cardiovascular risk factors and disease specific risk factors are inextricably intertwined in this particular case. Therefore, the cardiovascular risk profile in pSS is a multifaceted issue, sometimes difficult to assess. Furthermore, in the era of multimodality imaging, the diagnosis of subclinical myocardial and vascular damage is possible, with recent data pointing that the prevalence of such involvement is higher in pSS than in the general population. Nevertheless, when approaching patients with pSS in terms of cardiovascular diseases, clinicians are often faced with the difficult task of translating data from the literature into their everyday practice. The present review aims to synthesize the existing evidence on pSS associated cardiovascular changes in a clinically relevant manner. |
| first_indexed | 2024-04-13T20:16:10Z |
| format | Article |
| id | doaj.art-389df5071eab41db9269c4ce6ab8c072 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-04-13T20:16:10Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-389df5071eab41db9269c4ce6ab8c0722022-12-22T02:31:41ZengFrontiers Media S.A.Frontiers in Immunology1664-32242022-06-011310.3389/fimmu.2022.865373865373Cardiovascular Disease in Primary Sjögren’s Syndrome: Raising Clinicians’ AwarenessMihnea Casian0Mihnea Casian1Ciprian Jurcut2Alina Dima3Ancuta Mihai4Ancuta Mihai5Silviu Stanciu6Silviu Stanciu7Ruxandra Jurcut8Ruxandra Jurcut9Cardiology Department, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania2nd Internal Medicine Department, Central Military University Emergency Hospital, Bucharest, Romania2nd Internal Medicine Department, Central Military University Emergency Hospital, Bucharest, RomaniaDepartment of Rheumatology, Colentina Clinical Hospital, Bucharest, Romania2nd Internal Medicine Department, Central Military University Emergency Hospital, Bucharest, RomaniaRheumatology Department, University of Medicine and Pharmacy "Carol Davila", Bucharest, RomaniaCardiac Noninvasive Laboratory, Central Military University Emergency Hospital, Bucharest, RomaniaInternal Medicine Department, University of Medicine and Pharmacy "Carol Davila", Bucharest, RomaniaCardiology Department, University of Medicine and Pharmacy "Carol Davila", Bucharest, RomaniaDepartment of Cardiology, Expert Center for Rare Genetic Cardiovascular Diseases, Emergency Institute for Cardiovascular Diseases, Bucharest, RomaniaIn the ever evolving landscape of systemic immune mediated diseases, an increased awareness regarding the associated cardiovascular system impairment has been noted in recent years. Even though primary Sjögren’s Syndrome (pSS) is one of the most frequent autoimmune diseases affecting middle-aged individuals, the cardiovascular profile of this specific population is far less studied, at least compared to other autoimmune diseases. Traditional cardiovascular risk factors and disease specific risk factors are inextricably intertwined in this particular case. Therefore, the cardiovascular risk profile in pSS is a multifaceted issue, sometimes difficult to assess. Furthermore, in the era of multimodality imaging, the diagnosis of subclinical myocardial and vascular damage is possible, with recent data pointing that the prevalence of such involvement is higher in pSS than in the general population. Nevertheless, when approaching patients with pSS in terms of cardiovascular diseases, clinicians are often faced with the difficult task of translating data from the literature into their everyday practice. The present review aims to synthesize the existing evidence on pSS associated cardiovascular changes in a clinically relevant manner.https://www.frontiersin.org/articles/10.3389/fimmu.2022.865373/fullSjogren’ syndrome (SS)cardiovascular risk (CV risk)strain echocardiographyinflammationatherosclerosisautoimmune disease (AD) |
| spellingShingle | Mihnea Casian Mihnea Casian Ciprian Jurcut Alina Dima Ancuta Mihai Ancuta Mihai Silviu Stanciu Silviu Stanciu Ruxandra Jurcut Ruxandra Jurcut Cardiovascular Disease in Primary Sjögren’s Syndrome: Raising Clinicians’ Awareness Frontiers in Immunology Sjogren’ syndrome (SS) cardiovascular risk (CV risk) strain echocardiography inflammation atherosclerosis autoimmune disease (AD) |
| title | Cardiovascular Disease in Primary Sjögren’s Syndrome: Raising Clinicians’ Awareness |
| title_full | Cardiovascular Disease in Primary Sjögren’s Syndrome: Raising Clinicians’ Awareness |
| title_fullStr | Cardiovascular Disease in Primary Sjögren’s Syndrome: Raising Clinicians’ Awareness |
| title_full_unstemmed | Cardiovascular Disease in Primary Sjögren’s Syndrome: Raising Clinicians’ Awareness |
| title_short | Cardiovascular Disease in Primary Sjögren’s Syndrome: Raising Clinicians’ Awareness |
| title_sort | cardiovascular disease in primary sjogren s syndrome raising clinicians awareness |
| topic | Sjogren’ syndrome (SS) cardiovascular risk (CV risk) strain echocardiography inflammation atherosclerosis autoimmune disease (AD) |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2022.865373/full |
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