Breast Cancer in Women Younger than 35-Years-Old: Correlation of MRI Findings with Clinicopathological Features and Immunohistochemical Subtypes
Purpose Breast cancer of young women shows poor prognosis, but the imaging findings has not been well known. We evaluated the MRI characteristics of young women. Materials and Methods From January 2009 to December 2013, we included 91 patients under the age of 35 who were diagnosed histological...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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The Korean Society of Radiology
2018-10-01
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| Series: | 대한영상의학회지 |
| Subjects: | |
| Online Access: | https://doi.org/10.3348/jksr.2018.79.4.196 |
| _version_ | 1819105416081047552 |
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| author | Sae Hyung Lee Bong Joo Kang Yeong Yi An |
| author_facet | Sae Hyung Lee Bong Joo Kang Yeong Yi An |
| author_sort | Sae Hyung Lee |
| collection | DOAJ |
| description | Purpose
Breast cancer of young women shows poor prognosis, but the imaging findings has not been well known. We evaluated the MRI characteristics of young women.
Materials and Methods
From January 2009 to December 2013, we included 91 patients under the age of 35 who were diagnosed histologically as breast cancer and underwent MRI. The relationship between the clinical and histopathological prognostic factors was obtained using electronic medical records and the retrospective analysis of MRI findings was statistically analyzed.
Results
The most common imaging findings of breast mass were irregular shape (53.7%), irregular margin (53.7%), heterogeneous enhancement (53.8%), and type 3 kinetic curve pattern (57.1%). In the multivariate analysis, the rim enhancement was significantly related to the higher tissue grade (p = 0.001), estrogen receptor negative (p < 0.001), and progesterone receptor negative (p < 0.001). The irregular mass shape (p = 0.015) and type 3 kinetic curve (p = 0.002) were related to lymph node metastasis.
Conclusion
MRI findings of breast cancer in young women (≤ 35-years-old) are not different from those of general breast cancer, but the rim enhancement, irregular mass shape and type 3 kinetic curve are related with pathologic factors of poor prognosis. |
| first_indexed | 2024-12-22T02:21:54Z |
| format | Article |
| id | doaj.art-38a11744f3e1407da9b78e7732a50484 |
| institution | Directory Open Access Journal |
| issn | 1738-2637 2288-2928 |
| language | English |
| last_indexed | 2024-12-22T02:21:54Z |
| publishDate | 2018-10-01 |
| publisher | The Korean Society of Radiology |
| record_format | Article |
| series | 대한영상의학회지 |
| spelling | doaj.art-38a11744f3e1407da9b78e7732a504842022-12-21T18:42:07ZengThe Korean Society of Radiology대한영상의학회지1738-26372288-29282018-10-01794196203https://doi.org/10.3348/jksr.2018.79.4.196Breast Cancer in Women Younger than 35-Years-Old: Correlation of MRI Findings with Clinicopathological Features and Immunohistochemical SubtypesSae Hyung Lee0Bong Joo Kang1Yeong Yi An2Department of Radiology, St. Vincent's Hospital, College of Medicine, The Catholic Unversity of Korea, Suwon, KoreaDepartment of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Radiology, St. Vincent's Hospital, College of Medicine, The Catholic Unversity of Korea, Suwon, KoreaPurpose Breast cancer of young women shows poor prognosis, but the imaging findings has not been well known. We evaluated the MRI characteristics of young women. Materials and Methods From January 2009 to December 2013, we included 91 patients under the age of 35 who were diagnosed histologically as breast cancer and underwent MRI. The relationship between the clinical and histopathological prognostic factors was obtained using electronic medical records and the retrospective analysis of MRI findings was statistically analyzed. Results The most common imaging findings of breast mass were irregular shape (53.7%), irregular margin (53.7%), heterogeneous enhancement (53.8%), and type 3 kinetic curve pattern (57.1%). In the multivariate analysis, the rim enhancement was significantly related to the higher tissue grade (p = 0.001), estrogen receptor negative (p < 0.001), and progesterone receptor negative (p < 0.001). The irregular mass shape (p = 0.015) and type 3 kinetic curve (p = 0.002) were related to lymph node metastasis. Conclusion MRI findings of breast cancer in young women (≤ 35-years-old) are not different from those of general breast cancer, but the rim enhancement, irregular mass shape and type 3 kinetic curve are related with pathologic factors of poor prognosis.https://doi.org/10.3348/jksr.2018.79.4.196breast neoplasmsmagnetic resonance imagingmammographyultrasonographyyoung adult |
| spellingShingle | Sae Hyung Lee Bong Joo Kang Yeong Yi An Breast Cancer in Women Younger than 35-Years-Old: Correlation of MRI Findings with Clinicopathological Features and Immunohistochemical Subtypes 대한영상의학회지 breast neoplasms magnetic resonance imaging mammography ultrasonography young adult |
| title | Breast Cancer in Women Younger than 35-Years-Old: Correlation of MRI Findings with Clinicopathological Features and Immunohistochemical Subtypes |
| title_full | Breast Cancer in Women Younger than 35-Years-Old: Correlation of MRI Findings with Clinicopathological Features and Immunohistochemical Subtypes |
| title_fullStr | Breast Cancer in Women Younger than 35-Years-Old: Correlation of MRI Findings with Clinicopathological Features and Immunohistochemical Subtypes |
| title_full_unstemmed | Breast Cancer in Women Younger than 35-Years-Old: Correlation of MRI Findings with Clinicopathological Features and Immunohistochemical Subtypes |
| title_short | Breast Cancer in Women Younger than 35-Years-Old: Correlation of MRI Findings with Clinicopathological Features and Immunohistochemical Subtypes |
| title_sort | breast cancer in women younger than 35 years old correlation of mri findings with clinicopathological features and immunohistochemical subtypes |
| topic | breast neoplasms magnetic resonance imaging mammography ultrasonography young adult |
| url | https://doi.org/10.3348/jksr.2018.79.4.196 |
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