SARS-CoV-2 helicase NSP13 hijacks the host protein EWSR1 to promote viral replication by enhancing RNA unwinding activity

SARS-CoV-2 helicase NSP13 hijacks the host protein EWSR1 to promote viral replication by enhancing RNA unwinding activity

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and has led to a global coronavirus disease 2019 (COVID-19) pandemic. Currently, incomplete understanding of how SARS-CoV-2 arrogates the host cell to establish its life cycle has led to slow progress i...

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Bibliographic Details
Main Authors: Hongxiang Zeng, Xiang Gao, Gang Xu, Shengyuan Zhang, Lin Cheng, Tongyang Xiao, Wenhong Zu, Zheng Zhang
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Infectious Medicine
Subjects:
Nsp13
Ewsr1
Unwinding
Online Access:http://www.sciencedirect.com/science/article/pii/S2772431X22000065

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