DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration
Sk. Kayum Alam et al. show that DARPP-32 isoforms, mediators of dopamine signaling, promote lung tumor growth through non-canonical NF-κB signaling. This study suggests a possibility of using DARPP-32 isoforms as a prognostic marker for lung cancer.
Bibliographic Details
| Main Authors: |
Sk. Kayum Alam,
Matteo Astone,
Ping Liu,
Stephanie R. Hall,
Abbygail M. Coyle,
Erin N. Dankert,
Dane K. Hoffman,
Wei Zhang,
Rui Kuang,
Anja C. Roden,
Aaron S. Mansfield,
Luke H. Hoeppner |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2018-05-01
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| Series: | Communications Biology
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| Online Access: | https://doi.org/10.1038/s42003-018-0050-6
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