Effect of Oxygen and Water on the Stability of Imipenem and Cilastatin Sodium for Injection

Effect of Oxygen and Water on the Stability of Imipenem and Cilastatin Sodium for Injection

The study aimed to investigate the factors affecting the stability of imipenem and cilastatin sodium for injection (IMI/CIL) to improve the quality and stability in IMI/CIL preparation. In this study, the effects of headspace oxygen (HO), water content, particle shape, and particle size on the stabi...

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Bibliographic Details
Main Authors:	Meng Zhang, Chun-Feng Liu, Xiao-Yan Chen, Li-Na Yang, Chun-Mei Zhu, Jian-Hao Teng, Hao-Xiang Wu, Fu-Li Zhang
Format:	Article
Language:	English
Published:	Georg Thieme Verlag KG 2022-06-01
Series:	Pharmaceutical Fronts
Subjects:	imipenem cilastatin sodium stability oxidation free water
Online Access:	http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1750043

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