Remodeling of the Immune Response With Aging: Immunosenescence and Its Potential Impact on COVID-19 Immune Response

Remodeling of the Immune Response With Aging: Immunosenescence and Its Potential Impact on COVID-19 Immune Response

Elderly individuals are the most susceptible to an aggressive form of coronavirus disease (COVID-19), caused by SARS-CoV-2. The remodeling of immune response that is observed among the elderly could explain, at least in part, the age gradient in lethality of COVID-19. In this review, we will discuss...

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Bibliographic Details
Main Authors: Lucas Leite Cunha, Sandro Felix Perazzio, Jamil Azzi, Paolo Cravedi, Leonardo Vidal Riella
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
immunosenescence
inflammaging
SARS-CoV-2
COVID-19
immunopathogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01748/full

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