Clinical pharmacist intervention to ensure safe stimulant prescribing practices at a Veterans Affairs facility

Introduction The Psychotropic Drug Safety Initiative (PDSI) is a national Veterans Affairs program that recommends obtaining cardiovascular vital signs semiannually and urine toxicology screening annually for veterans prescribed stimulants. The PDSI also recommends a risk review of concurrent centra...

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Main Authors: Bailey B. Bass, PharmD, BCPS, Lacey J. Vann, PharmD, BCPP
Format: Article
Language:English
Published: American Association of Psychiatric Pharmacists 2024-02-01
Series:Mental Health Clinician
Subjects:
Online Access:https://theijpt.org/doi/pdf/10.9740/mhc.2024.02.017
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author Bailey B. Bass, PharmD, BCPS
Lacey J. Vann, PharmD, BCPP
author_facet Bailey B. Bass, PharmD, BCPS
Lacey J. Vann, PharmD, BCPP
author_sort Bailey B. Bass, PharmD, BCPS
collection DOAJ
description Introduction The Psychotropic Drug Safety Initiative (PDSI) is a national Veterans Affairs program that recommends obtaining cardiovascular vital signs semiannually and urine toxicology screening annually for veterans prescribed stimulants. The PDSI also recommends a risk review of concurrent central nervous system (CNS) depressants to ensure the benefits of coadministration with stimulants outweigh the risks. This project’s purpose was to evaluate the occurrence of coprescriptions for CNS depressants and stimulants and encourage compliance with the PDSI recommendations to increase safe and appropriate management of veterans prescribed the combination. This study aimed to evaluate the occurrence of coprescriptions for CNS depressants and stimulants, evaluate compliance with stimulant monitoring recommendations, and measure the proportion of pharmacist recommendations implemented by the prescriber. Methods This quality improvement project identified veterans with an outpatient prescription for a stimulant and any coprescription(s) for benzodiazepines, sedative-hypnotics, and/or opioids. A pharmacy intervention note was generated to request a risk review, provide recommendations for de-escalation, and notify the stimulant prescriber of overdue monitoring parameters. Impact was measured 60 days after intervention. Descriptive statistics and a McNemar test were used to compare preintervention and postintervention data. Results From the 61 patients included, there were 67 unique prescriptions for benzodiazepines (49.3%), sedative-hypnotics (34.3%), and opioids (16.4%) in combination with a stimulant. Pharmacist intervention resulted in de-escalation of coprescribing for 9 patients (16.1%) and was associated with statistically significant improvement in compliance to stimulant monitoring recommendations. Discussion Clinical pharmacists can assist in ensuring safe and appropriate monitoring and management of veterans prescribed stimulants.
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spelling doaj.art-38acf962d58247a6a6b88124facc314e2024-02-05T16:53:33ZengAmerican Association of Psychiatric PharmacistsMental Health Clinician2168-97092024-02-01141172210.9740/mhc.2024.02.017i2168-9709-14-1-17Clinical pharmacist intervention to ensure safe stimulant prescribing practices at a Veterans Affairs facilityBailey B. Bass, PharmD, BCPS0https://orcid.org/0000-0003-3409-3850Lacey J. Vann, PharmD, BCPP1https://orcid.org/0000-0002-4968-65471 PGY-2 Psychiatric Pharmacy Resident, Pharmacy Department, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina2 Mental Health Clinical Pharmacist Practitioner, Mental Health Department, Ralph H. Johnson Veterans Affairs Medical Center, Savannah, GeorgiaIntroduction The Psychotropic Drug Safety Initiative (PDSI) is a national Veterans Affairs program that recommends obtaining cardiovascular vital signs semiannually and urine toxicology screening annually for veterans prescribed stimulants. The PDSI also recommends a risk review of concurrent central nervous system (CNS) depressants to ensure the benefits of coadministration with stimulants outweigh the risks. This project’s purpose was to evaluate the occurrence of coprescriptions for CNS depressants and stimulants and encourage compliance with the PDSI recommendations to increase safe and appropriate management of veterans prescribed the combination. This study aimed to evaluate the occurrence of coprescriptions for CNS depressants and stimulants, evaluate compliance with stimulant monitoring recommendations, and measure the proportion of pharmacist recommendations implemented by the prescriber. Methods This quality improvement project identified veterans with an outpatient prescription for a stimulant and any coprescription(s) for benzodiazepines, sedative-hypnotics, and/or opioids. A pharmacy intervention note was generated to request a risk review, provide recommendations for de-escalation, and notify the stimulant prescriber of overdue monitoring parameters. Impact was measured 60 days after intervention. Descriptive statistics and a McNemar test were used to compare preintervention and postintervention data. Results From the 61 patients included, there were 67 unique prescriptions for benzodiazepines (49.3%), sedative-hypnotics (34.3%), and opioids (16.4%) in combination with a stimulant. Pharmacist intervention resulted in de-escalation of coprescribing for 9 patients (16.1%) and was associated with statistically significant improvement in compliance to stimulant monitoring recommendations. Discussion Clinical pharmacists can assist in ensuring safe and appropriate monitoring and management of veterans prescribed stimulants.https://theijpt.org/doi/pdf/10.9740/mhc.2024.02.017stimulantdrug interactionmonitoringsafetypharmacist
spellingShingle Bailey B. Bass, PharmD, BCPS
Lacey J. Vann, PharmD, BCPP
Clinical pharmacist intervention to ensure safe stimulant prescribing practices at a Veterans Affairs facility
Mental Health Clinician
stimulant
drug interaction
monitoring
safety
pharmacist
title Clinical pharmacist intervention to ensure safe stimulant prescribing practices at a Veterans Affairs facility
title_full Clinical pharmacist intervention to ensure safe stimulant prescribing practices at a Veterans Affairs facility
title_fullStr Clinical pharmacist intervention to ensure safe stimulant prescribing practices at a Veterans Affairs facility
title_full_unstemmed Clinical pharmacist intervention to ensure safe stimulant prescribing practices at a Veterans Affairs facility
title_short Clinical pharmacist intervention to ensure safe stimulant prescribing practices at a Veterans Affairs facility
title_sort clinical pharmacist intervention to ensure safe stimulant prescribing practices at a veterans affairs facility
topic stimulant
drug interaction
monitoring
safety
pharmacist
url https://theijpt.org/doi/pdf/10.9740/mhc.2024.02.017
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