The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa

Missed opportunities for vaccination (MOV) may be among the factors responsible for suboptimal vaccination coverage in South Africa. However, the magnitude and determinants of MOV in the country are not known. Thus, this study seeks to assess the prevalence and determinants of MOV in the country. So...

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Main Authors: Duduzile Ndwandwe, Chukwudi A. Nnaji, Charles S. Wiysonge
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/4/705
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author Duduzile Ndwandwe
Chukwudi A. Nnaji
Charles S. Wiysonge
author_facet Duduzile Ndwandwe
Chukwudi A. Nnaji
Charles S. Wiysonge
author_sort Duduzile Ndwandwe
collection DOAJ
description Missed opportunities for vaccination (MOV) may be among the factors responsible for suboptimal vaccination coverage in South Africa. However, the magnitude and determinants of MOV in the country are not known. Thus, this study seeks to assess the prevalence and determinants of MOV in the country. South Africa is sub-divided into nine administrative provinces. We used nationally representative data from the 2016 South African Demographic and Health Survey. We considered MOV to have occurred if a child aged 12–23 months old had not taken all scheduled basic vaccine doses despite having any of the following contacts with health services: delivery in a health facility; postnatal clinic visit; receipt of vitamin A; and any child-related treatment at a health facility. Multilevel logistic regression was used to determine factors associated with MOV. The national prevalence of MOV among children aged 12–23 months was 40.1%. Children whose mothers attended facility-based antenatal care were considerably less likely to experience MOV than those whose mothers did not attend antenatal care: odds ratio (OR) 0.41, 95% confidence interval (CI) 0.19 to 0.88. Conversely, the independent predictor of an increased MOV among children was residence in either the Gauteng province (OR 2.97, 95% CI 1.29 to 6.81) or Mpumalanga province (OR 2.32, 95%CI 1.04 to 5.18); compared to residence in the Free State province. Our findings suggest a high burden of MOV among children in South Africa and that MOV may be associated with individual and contextual factors. The findings also underscore the need for further exploration of the contextual factors contributing to MOV in South Africa.
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spelling doaj.art-38ae642d9d324fab90cf7f78d52157e42023-11-20T22:18:22ZengMDPI AGVaccines2076-393X2020-11-018470510.3390/vaccines8040705The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South AfricaDuduzile Ndwandwe0Chukwudi A. Nnaji1Charles S. Wiysonge2Cochrane South Africa, South African Medical Research Council, Francie Van Zijl Drive, Parow Valley, Cape Town 7501, South AfricaCochrane South Africa, South African Medical Research Council, Francie Van Zijl Drive, Parow Valley, Cape Town 7501, South AfricaCochrane South Africa, South African Medical Research Council, Francie Van Zijl Drive, Parow Valley, Cape Town 7501, South AfricaMissed opportunities for vaccination (MOV) may be among the factors responsible for suboptimal vaccination coverage in South Africa. However, the magnitude and determinants of MOV in the country are not known. Thus, this study seeks to assess the prevalence and determinants of MOV in the country. South Africa is sub-divided into nine administrative provinces. We used nationally representative data from the 2016 South African Demographic and Health Survey. We considered MOV to have occurred if a child aged 12–23 months old had not taken all scheduled basic vaccine doses despite having any of the following contacts with health services: delivery in a health facility; postnatal clinic visit; receipt of vitamin A; and any child-related treatment at a health facility. Multilevel logistic regression was used to determine factors associated with MOV. The national prevalence of MOV among children aged 12–23 months was 40.1%. Children whose mothers attended facility-based antenatal care were considerably less likely to experience MOV than those whose mothers did not attend antenatal care: odds ratio (OR) 0.41, 95% confidence interval (CI) 0.19 to 0.88. Conversely, the independent predictor of an increased MOV among children was residence in either the Gauteng province (OR 2.97, 95% CI 1.29 to 6.81) or Mpumalanga province (OR 2.32, 95%CI 1.04 to 5.18); compared to residence in the Free State province. Our findings suggest a high burden of MOV among children in South Africa and that MOV may be associated with individual and contextual factors. The findings also underscore the need for further exploration of the contextual factors contributing to MOV in South Africa.https://www.mdpi.com/2076-393X/8/4/705missed opportunities for vaccinationvaccination coverageSouth Africademographic and health surveylow- and middle-income countries
spellingShingle Duduzile Ndwandwe
Chukwudi A. Nnaji
Charles S. Wiysonge
The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
Vaccines
missed opportunities for vaccination
vaccination coverage
South Africa
demographic and health survey
low- and middle-income countries
title The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
title_full The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
title_fullStr The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
title_full_unstemmed The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
title_short The Magnitude and Determinants of Missed Opportunities for Childhood Vaccination in South Africa
title_sort magnitude and determinants of missed opportunities for childhood vaccination in south africa
topic missed opportunities for vaccination
vaccination coverage
South Africa
demographic and health survey
low- and middle-income countries
url https://www.mdpi.com/2076-393X/8/4/705
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