Mast cells are important modifiers of autoimmune disease: With so much evidence, why is there controversy?

There is abundant evidence that mast cells are active participants in events that mediate tissue damage in autoimmune disease. Disease-associated increases in mast cell numbers accompanied by mast cell degranulation and elaboration of numerous mast cell mediators at sites of inflammation are commonl...

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Bibliographic Details
Main Authors: Melissa Ann Brown, Julianne K Hatfield
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00147/full

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