Concomitant Guillain–Barré Syndrome in a young Sri Lankan male with severe ulcerative colitis
Abstract Background Guillain–Barré Syndrome is an immune mediated polyneuropathy. Ulcerative Colitis is an immune mediated chronic inflammatory condition mainly of the large intestine. Guillain–Barré Syndrome can present as a rare extraintestinal manifestation of Ulcerative Colitis when in remission...
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| Format: | Article |
| Language: | English |
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BMC
2022-09-01
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| Series: | BMC Gastroenterology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12876-022-02455-y |
| _version_ | 1818064835009576960 |
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| author | Jayasundara Mudiyanselage Hishali Dahami Jayasundara Vajira Tharanga Samarawickrama Ranjith Peiris Tilan Aponso Danushi Abeynayake |
| author_facet | Jayasundara Mudiyanselage Hishali Dahami Jayasundara Vajira Tharanga Samarawickrama Ranjith Peiris Tilan Aponso Danushi Abeynayake |
| author_sort | Jayasundara Mudiyanselage Hishali Dahami Jayasundara |
| collection | DOAJ |
| description | Abstract Background Guillain–Barré Syndrome is an immune mediated polyneuropathy. Ulcerative Colitis is an immune mediated chronic inflammatory condition mainly of the large intestine. Guillain–Barré Syndrome can present as a rare extraintestinal manifestation of Ulcerative Colitis when in remission or in a relapse. However, the concomitant presentation of Guillain–Barré Syndrome during a relapse of Ulcerative Colitis is very rare and only a few cases are reported to date. Case presentation A 24 year old young male diagnosed of Ulcerative Colitis presented with bloody diarrhea of frequency more than six times a day. He had been in clinical remission even after defaulting treatment for more than a year. He had also noted difficulty in walking prior to admission to the hospital. He was managed as for a severe relapse of Ulcerative Colitis and Guillain–Barré Syndrome. Appropriate management of both the illnesses helped him to recover. Conclusion Immune mediated diseases can have rare coexisting presentations. We report a case of Ulcerative Colitis with concomitant Guillain–Barré Syndrome. It is essential to be open minded and timely, appropriate treatment led to successful management of both the illnesses. |
| first_indexed | 2024-12-10T14:42:18Z |
| format | Article |
| id | doaj.art-38b81be3ba8745e2bbc615c0e0c504ac |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-12-10T14:42:18Z |
| publishDate | 2022-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj.art-38b81be3ba8745e2bbc615c0e0c504ac2022-12-22T01:44:40ZengBMCBMC Gastroenterology1471-230X2022-09-012211510.1186/s12876-022-02455-yConcomitant Guillain–Barré Syndrome in a young Sri Lankan male with severe ulcerative colitisJayasundara Mudiyanselage Hishali Dahami Jayasundara0Vajira Tharanga Samarawickrama1Ranjith Peiris2Tilan Aponso3Danushi Abeynayake4National Hospital of Sri LankaNational Hospital of Sri LankaNational Hospital of Sri LankaNational Hospital of Sri LankaNational Hospital of Sri LankaAbstract Background Guillain–Barré Syndrome is an immune mediated polyneuropathy. Ulcerative Colitis is an immune mediated chronic inflammatory condition mainly of the large intestine. Guillain–Barré Syndrome can present as a rare extraintestinal manifestation of Ulcerative Colitis when in remission or in a relapse. However, the concomitant presentation of Guillain–Barré Syndrome during a relapse of Ulcerative Colitis is very rare and only a few cases are reported to date. Case presentation A 24 year old young male diagnosed of Ulcerative Colitis presented with bloody diarrhea of frequency more than six times a day. He had been in clinical remission even after defaulting treatment for more than a year. He had also noted difficulty in walking prior to admission to the hospital. He was managed as for a severe relapse of Ulcerative Colitis and Guillain–Barré Syndrome. Appropriate management of both the illnesses helped him to recover. Conclusion Immune mediated diseases can have rare coexisting presentations. We report a case of Ulcerative Colitis with concomitant Guillain–Barré Syndrome. It is essential to be open minded and timely, appropriate treatment led to successful management of both the illnesses.https://doi.org/10.1186/s12876-022-02455-yUlcerative colitisGuillain–Barré SyndromeAcute Motor Axonal NeuropathyInflammatory bowel diseaseCase report |
| spellingShingle | Jayasundara Mudiyanselage Hishali Dahami Jayasundara Vajira Tharanga Samarawickrama Ranjith Peiris Tilan Aponso Danushi Abeynayake Concomitant Guillain–Barré Syndrome in a young Sri Lankan male with severe ulcerative colitis BMC Gastroenterology Ulcerative colitis Guillain–Barré Syndrome Acute Motor Axonal Neuropathy Inflammatory bowel disease Case report |
| title | Concomitant Guillain–Barré Syndrome in a young Sri Lankan male with severe ulcerative colitis |
| title_full | Concomitant Guillain–Barré Syndrome in a young Sri Lankan male with severe ulcerative colitis |
| title_fullStr | Concomitant Guillain–Barré Syndrome in a young Sri Lankan male with severe ulcerative colitis |
| title_full_unstemmed | Concomitant Guillain–Barré Syndrome in a young Sri Lankan male with severe ulcerative colitis |
| title_short | Concomitant Guillain–Barré Syndrome in a young Sri Lankan male with severe ulcerative colitis |
| title_sort | concomitant guillain barre syndrome in a young sri lankan male with severe ulcerative colitis |
| topic | Ulcerative colitis Guillain–Barré Syndrome Acute Motor Axonal Neuropathy Inflammatory bowel disease Case report |
| url | https://doi.org/10.1186/s12876-022-02455-y |
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