VISTA as a prospective immune checkpoint in gynecological malignant tumors: A review of the literature

VISTA as a prospective immune checkpoint in gynecological malignant tumors: A review of the literature

V-domain Ig suppressor of T cell activation (VISTA), encoded by the human VSIR gene, is a B7 family checkpoint homologous to the programmed death-Ligand 1 sequence. In gynecologic malignancies, VISTA is abnormally expressed and regulates the tumor immune microenvironment, causing a high upregulation...

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Bibliographic Details
Main Authors: Ren Ran, Chang Xin, Chen Cong, Yu Hao, Han Lu
Format: Article
Language:English
Published: De Gruyter 2023-12-01
Series:Open Medicine
Subjects:
vista
malignant tumors
tumor microenvironment
immunotherapy
Online Access:https://doi.org/10.1515/med-2023-0866

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