Progressive atherosclerosis in central India - A modern epidemic

Background: Atherosclerosis is the commonest and the most important of the arterial diseases commonly affecting aorta, coronaries and cerebral arterial systems. Objective: The present study was planned to know the prevalence of atherosclerosis in population of central India. Methods: The study durat...

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Main Authors: A.S. Keche, B.H. Tirpude, H.J. Bobade
Format: Article
Language:English
Published: Al Ameen Medical College 2013-10-01
Series:Al Ameen Journal of Medical Sciences
Subjects:
Online Access:http://ajms.alameenmedical.org/ArticlePDFs/AJMS%20V6.N4.2013%20p%20342-349.pdf
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author A.S. Keche
B.H. Tirpude
H.J. Bobade
author_facet A.S. Keche
B.H. Tirpude
H.J. Bobade
author_sort A.S. Keche
collection DOAJ
description Background: Atherosclerosis is the commonest and the most important of the arterial diseases commonly affecting aorta, coronaries and cerebral arterial systems. Objective: The present study was planned to know the prevalence of atherosclerosis in population of central India. Methods: The study duration was of 2 years from October 2006 to October 2008 & it includes 120 medicolegal postmortem cases. The atherosclerotic lesions if present in ascending aorta were noted. Related sections were taken from the areas for histopathological study. The major coronary arteries were sectioned transversely by sharp knife at intervals of not more than 0.3 cm as well as longitudinally and morphological lesions were noted. In each case sections were taken from coronary arteries and sent for histopathological study. Results & Conclusion: Overall prevalence of atherosclerosis was 74.2%. The percentage of affected arteries has shown a significantly rising trend with age, being highest in 60 and above age group (89.00%) and lowest in 10-19 years age group i.e.17.85%. The differences were also statistically significant. Males were affected more than females in all age groups. Advanced lesions were observed as early as in 3rd decade. As age advances more number of subjects was affected with atherosclerosis.
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spelling doaj.art-38bd4b5274f24fdeb312426e2643f5602022-12-22T00:52:00ZengAl Ameen Medical CollegeAl Ameen Journal of Medical Sciences0974-11432013-10-010604342349Progressive atherosclerosis in central India - A modern epidemicA.S. KecheB.H. TirpudeH.J. BobadeBackground: Atherosclerosis is the commonest and the most important of the arterial diseases commonly affecting aorta, coronaries and cerebral arterial systems. Objective: The present study was planned to know the prevalence of atherosclerosis in population of central India. Methods: The study duration was of 2 years from October 2006 to October 2008 & it includes 120 medicolegal postmortem cases. The atherosclerotic lesions if present in ascending aorta were noted. Related sections were taken from the areas for histopathological study. The major coronary arteries were sectioned transversely by sharp knife at intervals of not more than 0.3 cm as well as longitudinally and morphological lesions were noted. In each case sections were taken from coronary arteries and sent for histopathological study. Results & Conclusion: Overall prevalence of atherosclerosis was 74.2%. The percentage of affected arteries has shown a significantly rising trend with age, being highest in 60 and above age group (89.00%) and lowest in 10-19 years age group i.e.17.85%. The differences were also statistically significant. Males were affected more than females in all age groups. Advanced lesions were observed as early as in 3rd decade. As age advances more number of subjects was affected with atherosclerosis.http://ajms.alameenmedical.org/ArticlePDFs/AJMS%20V6.N4.2013%20p%20342-349.pdfAtherosclerosisPrevalenceCoronary arteriesAscending aorta
spellingShingle A.S. Keche
B.H. Tirpude
H.J. Bobade
Progressive atherosclerosis in central India - A modern epidemic
Al Ameen Journal of Medical Sciences
Atherosclerosis
Prevalence
Coronary arteries
Ascending aorta
title Progressive atherosclerosis in central India - A modern epidemic
title_full Progressive atherosclerosis in central India - A modern epidemic
title_fullStr Progressive atherosclerosis in central India - A modern epidemic
title_full_unstemmed Progressive atherosclerosis in central India - A modern epidemic
title_short Progressive atherosclerosis in central India - A modern epidemic
title_sort progressive atherosclerosis in central india a modern epidemic
topic Atherosclerosis
Prevalence
Coronary arteries
Ascending aorta
url http://ajms.alameenmedical.org/ArticlePDFs/AJMS%20V6.N4.2013%20p%20342-349.pdf
work_keys_str_mv AT askeche progressiveatherosclerosisincentralindiaamodernepidemic
AT bhtirpude progressiveatherosclerosisincentralindiaamodernepidemic
AT hjbobade progressiveatherosclerosisincentralindiaamodernepidemic