Targeting Cell Cycle Progression in HER2+ Breast Cancer: An Emerging Treatment Opportunity

Targeting Cell Cycle Progression in HER2+ Breast Cancer: An Emerging Treatment Opportunity

The development of HER2-targeted therapies has dramatically improved patient survival and patient management and increased the quality of life in the HER2+ breast cancer patient population. Due to the activation of compensatory pathways, patients eventually suffer from resistance to HER2-directed th...

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Bibliographic Details
Main Authors: Nischal Koirala, Nandini Dey, Jennifer Aske, Pradip De
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
brain metastasis
cell cycle inhibitors
cell cycle pathway
ERBB2
HER2+ breast cancer
HER2-targeted drug delivery
Online Access:https://www.mdpi.com/1422-0067/23/12/6547

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