Alpha transcranial alternating current stimulation modulates auditory perception
Background: Studies using transcranial alternating current stimulation (tACS), a type of non-invasive brain stimulation, have demonstrated a relationship between the positive versus negative phase of both alpha and delta/theta oscillations with variable near-threshold auditory perception. These find...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-11-01
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| Series: | Brain Stimulation |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1935861X23019459 |
| _version_ | 1797384123277377536 |
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| author | Sreekari Vogeti Maryam Faramarzi Christoph S. Herrmann |
| author_facet | Sreekari Vogeti Maryam Faramarzi Christoph S. Herrmann |
| author_sort | Sreekari Vogeti |
| collection | DOAJ |
| description | Background: Studies using transcranial alternating current stimulation (tACS), a type of non-invasive brain stimulation, have demonstrated a relationship between the positive versus negative phase of both alpha and delta/theta oscillations with variable near-threshold auditory perception. These findings have not been directly compared before. Furthermore, as perception was better in the positive versus negative phase of two different frequencies, it is unclear whether changes in polarity (independent of a specific frequency) could also modulate auditory perception. Objective: We investigated whether auditory perception depends on the phase of alpha, delta/theta, or polarity alone. Methods: We stimulated participants with alpha, delta, and positive and negative direct current (DC) over temporal and central scalp sites while they identified near-threshold tones-in-noise. A Sham condition without tACS served as a control condition. A repeated-measures analysis of variance was used to assess differences in proportions of hits between conditions and polarities. Permutation-based circular-logistic regressions were used to assess the relationship between circular-predictors and single-trial behavioral responses. An exploratory analysis compared the full circular-logistic regression model to the intercept-only model. Results: Overall, there were a greater proportion of hits in the Alpha condition in comparison to Delta, DC, and Sham conditions. We also found an interaction between polarity and stimulation condition; post-hoc analyses revealed a greater proportion of hits in the positive versus negative phase of Alpha tACS. In contrast, no significant differences were found in the Delta, DC, or Sham conditions. The permutation-based circular-logistic regressions did not reveal a statistically significant difference between the obtained RMS of the sine and cosine coefficients and the mean of the surrogate distribution for any of the conditions. However, our exploratory analysis revealed that circular-predictors explained the behavioral data significantly better than an intercept-only model for the Alpha condition, and not the other three conditions. Conclusion: These findings suggest that alpha tACS, and not delta nor polarity alone, modulates auditory perception. |
| first_indexed | 2024-03-08T21:30:56Z |
| format | Article |
| id | doaj.art-38c5a5bc7e724e979eec4849a2b967a3 |
| institution | Directory Open Access Journal |
| issn | 1935-861X |
| language | English |
| last_indexed | 2024-03-08T21:30:56Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brain Stimulation |
| spelling | doaj.art-38c5a5bc7e724e979eec4849a2b967a32023-12-21T07:30:06ZengElsevierBrain Stimulation1935-861X2023-11-0116616461652Alpha transcranial alternating current stimulation modulates auditory perceptionSreekari Vogeti0Maryam Faramarzi1Christoph S. Herrmann2Experimental Psychology Lab, Department of Psychology, European Medical School, Cluster for Excellence “Hearing for All”, Carl von Ossietzky University, Oldenburg, GermanyExperimental Psychology Lab, Department of Psychology, European Medical School, Cluster for Excellence “Hearing for All”, Carl von Ossietzky University, Oldenburg, GermanyExperimental Psychology Lab, Department of Psychology, European Medical School, Cluster for Excellence “Hearing for All”, Carl von Ossietzky University, Oldenburg, Germany; Neuroimaging Unit, European Medical School, Carl von Ossietzky University, Oldenburg, Germany; Research Center Neurosensory Science, Carl von Ossietzky University, Oldenburg, Germany; Corresponding author. Experimental Psychology Lab, Carl von Ossietzky University, Ammerländer Heerstr. 114 – 118, 26129, Oldenburg, Germany.Background: Studies using transcranial alternating current stimulation (tACS), a type of non-invasive brain stimulation, have demonstrated a relationship between the positive versus negative phase of both alpha and delta/theta oscillations with variable near-threshold auditory perception. These findings have not been directly compared before. Furthermore, as perception was better in the positive versus negative phase of two different frequencies, it is unclear whether changes in polarity (independent of a specific frequency) could also modulate auditory perception. Objective: We investigated whether auditory perception depends on the phase of alpha, delta/theta, or polarity alone. Methods: We stimulated participants with alpha, delta, and positive and negative direct current (DC) over temporal and central scalp sites while they identified near-threshold tones-in-noise. A Sham condition without tACS served as a control condition. A repeated-measures analysis of variance was used to assess differences in proportions of hits between conditions and polarities. Permutation-based circular-logistic regressions were used to assess the relationship between circular-predictors and single-trial behavioral responses. An exploratory analysis compared the full circular-logistic regression model to the intercept-only model. Results: Overall, there were a greater proportion of hits in the Alpha condition in comparison to Delta, DC, and Sham conditions. We also found an interaction between polarity and stimulation condition; post-hoc analyses revealed a greater proportion of hits in the positive versus negative phase of Alpha tACS. In contrast, no significant differences were found in the Delta, DC, or Sham conditions. The permutation-based circular-logistic regressions did not reveal a statistically significant difference between the obtained RMS of the sine and cosine coefficients and the mean of the surrogate distribution for any of the conditions. However, our exploratory analysis revealed that circular-predictors explained the behavioral data significantly better than an intercept-only model for the Alpha condition, and not the other three conditions. Conclusion: These findings suggest that alpha tACS, and not delta nor polarity alone, modulates auditory perception.http://www.sciencedirect.com/science/article/pii/S1935861X23019459Transcranial alternating current stimulation (tACS)1Oscillations2Entrainment3Hearing4Perception5Phase modulation6 |
| spellingShingle | Sreekari Vogeti Maryam Faramarzi Christoph S. Herrmann Alpha transcranial alternating current stimulation modulates auditory perception Brain Stimulation Transcranial alternating current stimulation (tACS)1 Oscillations2 Entrainment3 Hearing4 Perception5 Phase modulation6 |
| title | Alpha transcranial alternating current stimulation modulates auditory perception |
| title_full | Alpha transcranial alternating current stimulation modulates auditory perception |
| title_fullStr | Alpha transcranial alternating current stimulation modulates auditory perception |
| title_full_unstemmed | Alpha transcranial alternating current stimulation modulates auditory perception |
| title_short | Alpha transcranial alternating current stimulation modulates auditory perception |
| title_sort | alpha transcranial alternating current stimulation modulates auditory perception |
| topic | Transcranial alternating current stimulation (tACS)1 Oscillations2 Entrainment3 Hearing4 Perception5 Phase modulation6 |
| url | http://www.sciencedirect.com/science/article/pii/S1935861X23019459 |
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