Cardiovascular rhythmicity in overweight and obese children
Abstract Introduction: Obesity is thought to play a role in the disruption of cardiac rhythmicity in obese children, but this is mostly an unexplored field of investigation. We aimed to evaluate the impact of overweight and obesity on circadian and ultradian cardiovascular rhythmicity of prepuberta...
| Autors principals: | , , , , , , , , , , |
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| Format: | Article |
| Idioma: | English |
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Sociedade Brasileira de Nefrologia
2023-07-01
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| Col·lecció: | Brazilian Journal of Nephrology |
| Matèries: | |
| Accés en línia: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002023005027502&lng=en&tlng=en |
| _version_ | 1827888937465544704 |
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| author | Catarina Pinto-Silva Ana Correia-Costa Cláudia Moura Cláudia Mota António Guerra José Carlos Areias Franz Schaefer Alberto Caldas Afonso Elke Wühl Ana Azevedo Liane Correia-Costa |
| author_facet | Catarina Pinto-Silva Ana Correia-Costa Cláudia Moura Cláudia Mota António Guerra José Carlos Areias Franz Schaefer Alberto Caldas Afonso Elke Wühl Ana Azevedo Liane Correia-Costa |
| author_sort | Catarina Pinto-Silva |
| collection | DOAJ |
| description | Abstract Introduction: Obesity is thought to play a role in the disruption of cardiac rhythmicity in obese children, but this is mostly an unexplored field of investigation. We aimed to evaluate the impact of overweight and obesity on circadian and ultradian cardiovascular rhythmicity of prepubertal children, in comparison with normal weight counterparts. Methods: We performed a cross sectional study of 316 children, followed in the birth cohort Generation XXI (Portugal). Anthropometrics and 24-hour ambulatory blood pressure were measured and profiles were examined with Fourier analysis for circadian and ultradian blood pressure (BP) and heart rate (HR) rhythms. Results: Overweight/obese children presented more frequently a non-dipping BP pattern than normal weight counterparts (31.5% vs. 21.6%, p = 0.047). The prevalence of 24-hour mean arterial pressure (MAP) and 8-hour HR rhythmicity was significantly lower in obese children (79.3% vs. 88.0%, p = 0.038 and 33.3% vs. 45.2%, p = 0.031, respectively). The prevalence of the remaining MAP and HR rhythmicity was similar in both groups. No differences were found in the median values of amplitudes and acrophases of MAP and HR rhythms. Discussion: The alterations found in rhythmicity suggest that circadian and ultradian rhythmicity analysis might be sensitive in detecting early cardiovascular dysregulations, but future studies are needed to reinforce our findings and to better understand their long-term implications. |
| first_indexed | 2024-03-12T20:44:58Z |
| format | Article |
| id | doaj.art-38c735b3283e40b3b6f901b3db97b342 |
| institution | Directory Open Access Journal |
| issn | 2175-8239 |
| language | English |
| last_indexed | 2024-03-12T20:44:58Z |
| publishDate | 2023-07-01 |
| publisher | Sociedade Brasileira de Nefrologia |
| record_format | Article |
| series | Brazilian Journal of Nephrology |
| spelling | doaj.art-38c735b3283e40b3b6f901b3db97b3422023-08-01T07:45:12ZengSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology2175-82392023-07-0110.1590/2175-8239-jbn-2022-0138enCardiovascular rhythmicity in overweight and obese childrenCatarina Pinto-Silvahttps://orcid.org/0000-0001-6728-4149Ana Correia-Costahttps://orcid.org/0000-0002-3197-5842Cláudia MouraCláudia Motahttps://orcid.org/0009-0005-7888-2351António Guerrahttps://orcid.org/0000-0002-7951-3911José Carlos Areiashttps://orcid.org/0000-0002-9833-2518Franz Schaeferhttps://orcid.org/0000-0001-7564-9937Alberto Caldas Afonsohttps://orcid.org/0000-0002-2574-4132Elke Wühlhttps://orcid.org/0000-0002-1205-2620Ana Azevedohttps://orcid.org/0000-0002-7368-9609Liane Correia-Costahttps://orcid.org/0000-0002-8216-090XAbstract Introduction: Obesity is thought to play a role in the disruption of cardiac rhythmicity in obese children, but this is mostly an unexplored field of investigation. We aimed to evaluate the impact of overweight and obesity on circadian and ultradian cardiovascular rhythmicity of prepubertal children, in comparison with normal weight counterparts. Methods: We performed a cross sectional study of 316 children, followed in the birth cohort Generation XXI (Portugal). Anthropometrics and 24-hour ambulatory blood pressure were measured and profiles were examined with Fourier analysis for circadian and ultradian blood pressure (BP) and heart rate (HR) rhythms. Results: Overweight/obese children presented more frequently a non-dipping BP pattern than normal weight counterparts (31.5% vs. 21.6%, p = 0.047). The prevalence of 24-hour mean arterial pressure (MAP) and 8-hour HR rhythmicity was significantly lower in obese children (79.3% vs. 88.0%, p = 0.038 and 33.3% vs. 45.2%, p = 0.031, respectively). The prevalence of the remaining MAP and HR rhythmicity was similar in both groups. No differences were found in the median values of amplitudes and acrophases of MAP and HR rhythms. Discussion: The alterations found in rhythmicity suggest that circadian and ultradian rhythmicity analysis might be sensitive in detecting early cardiovascular dysregulations, but future studies are needed to reinforce our findings and to better understand their long-term implications.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002023005027502&lng=en&tlng=enPediatric ObesityCircadian RhythmUltradian Rhythm |
| spellingShingle | Catarina Pinto-Silva Ana Correia-Costa Cláudia Moura Cláudia Mota António Guerra José Carlos Areias Franz Schaefer Alberto Caldas Afonso Elke Wühl Ana Azevedo Liane Correia-Costa Cardiovascular rhythmicity in overweight and obese children Brazilian Journal of Nephrology Pediatric Obesity Circadian Rhythm Ultradian Rhythm |
| title | Cardiovascular rhythmicity in overweight and obese children |
| title_full | Cardiovascular rhythmicity in overweight and obese children |
| title_fullStr | Cardiovascular rhythmicity in overweight and obese children |
| title_full_unstemmed | Cardiovascular rhythmicity in overweight and obese children |
| title_short | Cardiovascular rhythmicity in overweight and obese children |
| title_sort | cardiovascular rhythmicity in overweight and obese children |
| topic | Pediatric Obesity Circadian Rhythm Ultradian Rhythm |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002023005027502&lng=en&tlng=en |
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