Epithelial-to-mesenchymal transition proceeds through directional destabilization of multidimensional attractor
How a cell changes from one stable phenotype to another one is a fundamental problem in developmental and cell biology. Mathematically, a stable phenotype corresponds to a stable attractor in a generally multi-dimensional state space, which needs to be destabilized so the cell relaxes to a new attra...
Main Authors: | Weikang Wang, Dante Poe, Yaxuan Yang, Thomas Hyatt, Jianhua Xing |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/74866 |
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