Epithelial-to-mesenchymal transition proceeds through directional destabilization of multidimensional attractor

How a cell changes from one stable phenotype to another one is a fundamental problem in developmental and cell biology. Mathematically, a stable phenotype corresponds to a stable attractor in a generally multi-dimensional state space, which needs to be destabilized so the cell relaxes to a new attra...

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Bibliographic Details
Main Authors: Weikang Wang, Dante Poe, Yaxuan Yang, Thomas Hyatt, Jianhua Xing
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/74866

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