Lamprey VLRB response to influenza virus supports universal rules of immunogenicity and antigenicity

Lamprey VLRB response to influenza virus supports universal rules of immunogenicity and antigenicity

Immunoglobulins (Igs) are a crown jewel of jawed vertebrate evolution. Through recombination and mutation of small numbers of genes, Igs can specifically recognize a vast variety of natural and man-made organic molecules. Jawless vertebrates evolved a parallel system of humoral immunity, which recog...

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Bibliographic Details
Main Authors: Meghan O Altman, Jack R Bennink, Jonathan W Yewdell, Brantley R Herrin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-08-01
Series:eLife
Subjects:
lamprey
immunodominance
antibodies
antigenicity
influenza
hemagglutinin
Online Access:https://elifesciences.org/articles/07467

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