Associations of vascular calcification, calcium phosphate disturbances, FGF 23 and Matrix Gla protein with mortality of hemodialysis patients: one center cohort study

Background and objectives: Vascular calcification (VC) is one of the factors associated with mortality in hemodialysis (HD) patients. The purpose of the study was to assess associations between prevalent VC and disturbances of calcium-phosphate metabolism as well as changes in vitamin D (25(OH)D), F...

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Main Authors: Petrauskiene Vaida, Vaiciuniene Ruta, Kuzminskis Vytautas, Ziginskiene Edita, Grazulis Saulius, Jonaitiene Egle, Skrodeniene Erika, Bumblyte Inga Arune
Format: Article
Language:English
Published: Sciendo 2018-10-01
Series:Romanian Journal of Laboratory Medicine
Subjects:
Online Access:https://doi.org/10.2478/rrlm-2018-0034
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author Petrauskiene Vaida
Vaiciuniene Ruta
Kuzminskis Vytautas
Ziginskiene Edita
Grazulis Saulius
Jonaitiene Egle
Skrodeniene Erika
Bumblyte Inga Arune
author_facet Petrauskiene Vaida
Vaiciuniene Ruta
Kuzminskis Vytautas
Ziginskiene Edita
Grazulis Saulius
Jonaitiene Egle
Skrodeniene Erika
Bumblyte Inga Arune
author_sort Petrauskiene Vaida
collection DOAJ
description Background and objectives: Vascular calcification (VC) is one of the factors associated with mortality in hemodialysis (HD) patients. The purpose of the study was to assess associations between prevalent VC and disturbances of calcium-phosphate metabolism as well as changes in vitamin D (25(OH)D), FGF 23 and MGP levels and to evaluate the possible impact of VC and changes of these biomarkers on survival in HD patients.
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spelling doaj.art-38cac09e8524423da74dfce2d3f309e62022-12-21T21:29:47ZengSciendoRomanian Journal of Laboratory Medicine2284-56232018-10-0126445146010.2478/rrlm-2018-0034rrlm-2018-0034Associations of vascular calcification, calcium phosphate disturbances, FGF 23 and Matrix Gla protein with mortality of hemodialysis patients: one center cohort studyPetrauskiene Vaida0Vaiciuniene Ruta1Kuzminskis Vytautas2Ziginskiene Edita3Grazulis Saulius4Jonaitiene Egle5Skrodeniene Erika6Bumblyte Inga Arune7Department of Nephrology, Medical Academy, Lithuanian University of Health Sciences, LithuaniaDepartment of Nephrology, Medical Academy, Lithuanian University of Health Sciences, LithuaniaDepartment of Nephrology, Medical Academy, Lithuanian University of Health Sciences, LithuaniaDepartment of Nephrology, Medical Academy, Lithuanian University of Health Sciences, LithuaniaDepartment of Nephrology, Medical Academy, Lithuanian University of Health Sciences, LithuaniaDepartment of Radiology, Medical Academy, Lithuanian University of Health Sciences, LithuaniaDepartment of Laboratory medicine, Medical Academy, Lithuanian University of Health Sciences, LithuaniaDepartment of Nephrology, Medical Academy, Lithuanian University of Health Sciences, LithuaniaBackground and objectives: Vascular calcification (VC) is one of the factors associated with mortality in hemodialysis (HD) patients. The purpose of the study was to assess associations between prevalent VC and disturbances of calcium-phosphate metabolism as well as changes in vitamin D (25(OH)D), FGF 23 and MGP levels and to evaluate the possible impact of VC and changes of these biomarkers on survival in HD patients.https://doi.org/10.2478/rrlm-2018-0034mineral metabolism disordersfgf 23mgphemodialysissurvival
spellingShingle Petrauskiene Vaida
Vaiciuniene Ruta
Kuzminskis Vytautas
Ziginskiene Edita
Grazulis Saulius
Jonaitiene Egle
Skrodeniene Erika
Bumblyte Inga Arune
Associations of vascular calcification, calcium phosphate disturbances, FGF 23 and Matrix Gla protein with mortality of hemodialysis patients: one center cohort study
Romanian Journal of Laboratory Medicine
mineral metabolism disorders
fgf 23
mgp
hemodialysis
survival
title Associations of vascular calcification, calcium phosphate disturbances, FGF 23 and Matrix Gla protein with mortality of hemodialysis patients: one center cohort study
title_full Associations of vascular calcification, calcium phosphate disturbances, FGF 23 and Matrix Gla protein with mortality of hemodialysis patients: one center cohort study
title_fullStr Associations of vascular calcification, calcium phosphate disturbances, FGF 23 and Matrix Gla protein with mortality of hemodialysis patients: one center cohort study
title_full_unstemmed Associations of vascular calcification, calcium phosphate disturbances, FGF 23 and Matrix Gla protein with mortality of hemodialysis patients: one center cohort study
title_short Associations of vascular calcification, calcium phosphate disturbances, FGF 23 and Matrix Gla protein with mortality of hemodialysis patients: one center cohort study
title_sort associations of vascular calcification calcium phosphate disturbances fgf 23 and matrix gla protein with mortality of hemodialysis patients one center cohort study
topic mineral metabolism disorders
fgf 23
mgp
hemodialysis
survival
url https://doi.org/10.2478/rrlm-2018-0034
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