Novel Antibacterial Modification of Polycarbonate for Increment Prototyping in Medicine
In the era of modern medicine, the number of invasive treatments increases. Artificial devices used in medicine are associated with an increased risk of secondary infections. Bacterial biofilm development observed on the implanted surface is challenging to treat, primarily due to low antibiotics pen...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/14/16/4725 |
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| author | Tomasz Flak Ewa Trejnowska Szymon Skoczyński Jadwiga Gabor Beata Swinarew Klaudia Grzywnowicz Hubert Okła Krzysztof Jasik Arkadiusz Stanula Grzegorz Brożek Andrzej S. Swinarew |
| author_facet | Tomasz Flak Ewa Trejnowska Szymon Skoczyński Jadwiga Gabor Beata Swinarew Klaudia Grzywnowicz Hubert Okła Krzysztof Jasik Arkadiusz Stanula Grzegorz Brożek Andrzej S. Swinarew |
| author_sort | Tomasz Flak |
| collection | DOAJ |
| description | In the era of modern medicine, the number of invasive treatments increases. Artificial devices used in medicine are associated with an increased risk of secondary infections. Bacterial biofilm development observed on the implanted surface is challenging to treat, primarily due to low antibiotics penetration. In our study, the preparation of a new polycarbonate composite, filled with nanosilver, nanosilica and rhodamine B derivative, suitable for three-dimensional printing, is described. Polymer materials with antimicrobial properties are known. However, in most cases, protection is limited to the outer layers only. The newly developed materials are protected in their entire volume. Moreover, the antibacterial properties are retained after multiple high-temperature processing were performed, allowing them to be used in 3D printing. Bacterial population reduction was observed, which gives an assumption for those materials to be clinically tested in the production of various medical devices and for the reduction of morbidity and mortality caused by multidrug-resistant bacteria. |
| first_indexed | 2024-03-10T08:37:54Z |
| format | Article |
| id | doaj.art-38ccc79f9ac14de2bce319d72f0847fe |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T08:37:54Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-38ccc79f9ac14de2bce319d72f0847fe2023-11-22T08:31:57ZengMDPI AGMaterials1996-19442021-08-011416472510.3390/ma14164725Novel Antibacterial Modification of Polycarbonate for Increment Prototyping in MedicineTomasz Flak0Ewa Trejnowska1Szymon Skoczyński2Jadwiga Gabor3Beata Swinarew4Klaudia Grzywnowicz5Hubert Okła6Krzysztof Jasik7Arkadiusz Stanula8Grzegorz Brożek9Andrzej S. Swinarew10Faculty of Science and Technology, University of Silesia in Katowice, 40-007 Katowice, PolandDepartment of Cardiac Anesthesia and Intensive Therapy, Silesian Centre for Heart Diseases, Zabrze, Medical University of Silesia, 40-752 Katowice, PolandDepartment of Pneumonology, School of Medicine in Katowice, Medical University of Silesia, 40-752 Katowice, PolandFaculty of Science and Technology, University of Silesia in Katowice, 40-007 Katowice, PolandLukasiewicz Research Network—Institute for Engineering of Polymer Materials and Dyes, 44-100 Gliwice, PolandFaculty of Science and Technology, University of Silesia in Katowice, 40-007 Katowice, PolandFaculty of Science and Technology, University of Silesia in Katowice, 40-007 Katowice, PolandDepartment of Pathology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 40-752 Katowice, PolandInstitute of Sport Science, The Jerzy Kukuczka Academy of Physical Education, 40-065 Katowice, PolandDepartment of Epidemiology, School of Medicine in Katowice, Medical University of Silesia Katowice, 40-752 Katowice, PolandFaculty of Science and Technology, University of Silesia in Katowice, 40-007 Katowice, PolandIn the era of modern medicine, the number of invasive treatments increases. Artificial devices used in medicine are associated with an increased risk of secondary infections. Bacterial biofilm development observed on the implanted surface is challenging to treat, primarily due to low antibiotics penetration. In our study, the preparation of a new polycarbonate composite, filled with nanosilver, nanosilica and rhodamine B derivative, suitable for three-dimensional printing, is described. Polymer materials with antimicrobial properties are known. However, in most cases, protection is limited to the outer layers only. The newly developed materials are protected in their entire volume. Moreover, the antibacterial properties are retained after multiple high-temperature processing were performed, allowing them to be used in 3D printing. Bacterial population reduction was observed, which gives an assumption for those materials to be clinically tested in the production of various medical devices and for the reduction of morbidity and mortality caused by multidrug-resistant bacteria.https://www.mdpi.com/1996-1944/14/16/4725polycarbonatebacterial biofilmantibacterial activityhealthcare-related infection |
| spellingShingle | Tomasz Flak Ewa Trejnowska Szymon Skoczyński Jadwiga Gabor Beata Swinarew Klaudia Grzywnowicz Hubert Okła Krzysztof Jasik Arkadiusz Stanula Grzegorz Brożek Andrzej S. Swinarew Novel Antibacterial Modification of Polycarbonate for Increment Prototyping in Medicine Materials polycarbonate bacterial biofilm antibacterial activity healthcare-related infection |
| title | Novel Antibacterial Modification of Polycarbonate for Increment Prototyping in Medicine |
| title_full | Novel Antibacterial Modification of Polycarbonate for Increment Prototyping in Medicine |
| title_fullStr | Novel Antibacterial Modification of Polycarbonate for Increment Prototyping in Medicine |
| title_full_unstemmed | Novel Antibacterial Modification of Polycarbonate for Increment Prototyping in Medicine |
| title_short | Novel Antibacterial Modification of Polycarbonate for Increment Prototyping in Medicine |
| title_sort | novel antibacterial modification of polycarbonate for increment prototyping in medicine |
| topic | polycarbonate bacterial biofilm antibacterial activity healthcare-related infection |
| url | https://www.mdpi.com/1996-1944/14/16/4725 |
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