The feasibility of an exercise intervention after robotic-assisted radical cystectomy for urinary bladder cancer, prior to the CanMoRe trial
Abstract Background Complications after radical cystectomy for urinary bladder cancer are common. Physical activity after surgery is thought to reduce complications. However, patients with urinary bladder cancer have low levels of physical activity, and interventions supporting physical exercise are...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | Pilot and Feasibility Studies |
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| Online Access: | https://doi.org/10.1186/s40814-024-01443-1 |
| _version_ | 1797340276310671360 |
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| author | Andrea Porserud Patrik Karlsson Malin Nygren-Bonnier Markus Aly Maria Hagströmer |
| author_facet | Andrea Porserud Patrik Karlsson Malin Nygren-Bonnier Markus Aly Maria Hagströmer |
| author_sort | Andrea Porserud |
| collection | DOAJ |
| description | Abstract Background Complications after radical cystectomy for urinary bladder cancer are common. Physical activity after surgery is thought to reduce complications. However, patients with urinary bladder cancer have low levels of physical activity, and interventions supporting physical exercise are needed. This study aimed to evaluate the feasibility of a physical exercise intervention in primary health care. One of the aims of the larger clinical trial will be to reduce complications. Methods Patients with urinary bladder cancer and who were scheduled for a robotic-assisted radical cystectomy were recruited from Karolinska University Hospital, between February and May 2019. The patients had to be mobile, understand Swedish, and live in Stockholm. The exercise programme was conducted at one primary health care setting over 12 weeks. The exercise programme included supervised aerobic and strengthening exercises, which were performed twice a week, as well as daily walks. Feasibility was measured with process feasibility, including eligibility criteria, adherence, and acceptability, and scientific feasibility, including the ability of outcomes to indicate change, safety, and progression in the exercise programme. Results Ten patients with a median age of 70 years (min 53–max 86) were included. Adherence to all parts of the intervention was not feasible because of patients’ postoperative complications, resulting in dropouts. For the patients who took part in the exercise programme, adherence and acceptability for the exercise period were feasible, but the 6-min walk test was not feasible at discharge from the hospital. Physiotherapists in the primary health care setting perceived the process as feasible. Moreover, the ability of outcomes to indicate change and progression in the exercise programme was feasible, meanwhile no adverse events were registered. Conclusions The exercise intervention was feasible for the patients that took part in the exercise programme, with respect to safety and progression through the exercise programme. Furthermore, this study suggests that some improvements needed to be implemented in the process, prior to the upcoming randomised controlled trial. |
| first_indexed | 2024-03-08T10:00:39Z |
| format | Article |
| id | doaj.art-38cde36a5f8c420481faaf234513ca29 |
| institution | Directory Open Access Journal |
| issn | 2055-5784 |
| language | English |
| last_indexed | 2024-03-08T10:00:39Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Pilot and Feasibility Studies |
| spelling | doaj.art-38cde36a5f8c420481faaf234513ca292024-01-29T10:58:31ZengBMCPilot and Feasibility Studies2055-57842024-01-0110111210.1186/s40814-024-01443-1The feasibility of an exercise intervention after robotic-assisted radical cystectomy for urinary bladder cancer, prior to the CanMoRe trialAndrea Porserud0Patrik Karlsson1Malin Nygren-Bonnier2Markus Aly3Maria Hagströmer4Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska InstitutetDivision of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska InstitutetDivision of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska InstitutetDepartment of Molecular Medicine and Surgery, Karolinska InstitutetDivision of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska InstitutetAbstract Background Complications after radical cystectomy for urinary bladder cancer are common. Physical activity after surgery is thought to reduce complications. However, patients with urinary bladder cancer have low levels of physical activity, and interventions supporting physical exercise are needed. This study aimed to evaluate the feasibility of a physical exercise intervention in primary health care. One of the aims of the larger clinical trial will be to reduce complications. Methods Patients with urinary bladder cancer and who were scheduled for a robotic-assisted radical cystectomy were recruited from Karolinska University Hospital, between February and May 2019. The patients had to be mobile, understand Swedish, and live in Stockholm. The exercise programme was conducted at one primary health care setting over 12 weeks. The exercise programme included supervised aerobic and strengthening exercises, which were performed twice a week, as well as daily walks. Feasibility was measured with process feasibility, including eligibility criteria, adherence, and acceptability, and scientific feasibility, including the ability of outcomes to indicate change, safety, and progression in the exercise programme. Results Ten patients with a median age of 70 years (min 53–max 86) were included. Adherence to all parts of the intervention was not feasible because of patients’ postoperative complications, resulting in dropouts. For the patients who took part in the exercise programme, adherence and acceptability for the exercise period were feasible, but the 6-min walk test was not feasible at discharge from the hospital. Physiotherapists in the primary health care setting perceived the process as feasible. Moreover, the ability of outcomes to indicate change and progression in the exercise programme was feasible, meanwhile no adverse events were registered. Conclusions The exercise intervention was feasible for the patients that took part in the exercise programme, with respect to safety and progression through the exercise programme. Furthermore, this study suggests that some improvements needed to be implemented in the process, prior to the upcoming randomised controlled trial.https://doi.org/10.1186/s40814-024-01443-1Complex interventionPhysical activityPhysiotherapyPostoperative complicationsPrimary health care |
| spellingShingle | Andrea Porserud Patrik Karlsson Malin Nygren-Bonnier Markus Aly Maria Hagströmer The feasibility of an exercise intervention after robotic-assisted radical cystectomy for urinary bladder cancer, prior to the CanMoRe trial Pilot and Feasibility Studies Complex intervention Physical activity Physiotherapy Postoperative complications Primary health care |
| title | The feasibility of an exercise intervention after robotic-assisted radical cystectomy for urinary bladder cancer, prior to the CanMoRe trial |
| title_full | The feasibility of an exercise intervention after robotic-assisted radical cystectomy for urinary bladder cancer, prior to the CanMoRe trial |
| title_fullStr | The feasibility of an exercise intervention after robotic-assisted radical cystectomy for urinary bladder cancer, prior to the CanMoRe trial |
| title_full_unstemmed | The feasibility of an exercise intervention after robotic-assisted radical cystectomy for urinary bladder cancer, prior to the CanMoRe trial |
| title_short | The feasibility of an exercise intervention after robotic-assisted radical cystectomy for urinary bladder cancer, prior to the CanMoRe trial |
| title_sort | feasibility of an exercise intervention after robotic assisted radical cystectomy for urinary bladder cancer prior to the canmore trial |
| topic | Complex intervention Physical activity Physiotherapy Postoperative complications Primary health care |
| url | https://doi.org/10.1186/s40814-024-01443-1 |
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