1α,25(OH)2D3 Induces Actin Depolymerization in Endometrial Carcinoma Cells by Targeting RAC1 and PAK1

1α,25(OH)2D3 Induces Actin Depolymerization in Endometrial Carcinoma Cells by Targeting RAC1 and PAK1

Background: Cell proliferation and motility require actin reorganization, which is under control of various signalling pathways including ras-related C3 botulinum toxin substrate 1 (RAC1), p21 protein-activated kinase 1 (PAK1) and actin related protein 2 (ARP2). Tumour cell proliferation is modified...

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Bibliographic Details
Main Authors: Ni Zeng, Madhuri S. Salker, Shaqiu Zhang, Yogesh Singh, Bing Shi, Christos Stournaras, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Actin polymerization
RAC1
PAK1
Endometrium
Tumour cells
Online Access:http://www.karger.com/Article/FullText/453197

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