TRPM8 Channel Activation Reduces the Spontaneous Contractions in Human Distal Colon

The transient receptor potential-melastatin 8 (TRPM8) is a non-selective Ca<sup>2+</sup>-permeable channel, activated by cold, membrane depolarization, and different cooling compounds. TRPM8 expression has been found in gut mucosal, submucosal, and muscular nerve endings. Although TRPM8...

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Bibliographic Details
Main Authors: Antonella Amato, Simona Terzo, Laura Lentini, Pierenrico Marchesa, Flavia Mulè
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/15/5403

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