Risk Factors Associated with Major Complications after Ultrasound-Guided Percutaneous Renal Biopsy of Native Kidneys
Introduction: Percutaneous renal biopsy (PRB) of native kidneys is an important tool for diagnosis and management of renal disease. In this study, we analyzed the success, safety, and risk complications of PRB in our center. Methods: A retrospective review of ultrasound-guided PRB done at our instit...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2019-12-01
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| Series: | Kidney & Blood Pressure Research |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/504544 |
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| author | Beatriz Pombas Eva Rodríguez Juan Sánchez Aleksandar Radosevic Javier Gimeno Marcos Busto Clara Barrios Laia Sans Julio Pascual María José Soler |
| author_facet | Beatriz Pombas Eva Rodríguez Juan Sánchez Aleksandar Radosevic Javier Gimeno Marcos Busto Clara Barrios Laia Sans Julio Pascual María José Soler |
| author_sort | Beatriz Pombas |
| collection | DOAJ |
| description | Introduction: Percutaneous renal biopsy (PRB) of native kidneys is an important tool for diagnosis and management of renal disease. In this study, we analyzed the success, safety, and risk complications of PRB in our center. Methods: A retrospective review of ultrasound-guided PRB done at our institution from January 1998 to December 2017 was performed. Clinical and laboratory data were collected for 661 PRBs. Statistical analysis was performed using the Mann-Whitney U test for continuous variable and chi-square test for categorical variables. Multivariate analysis using logistic regression was performed to assess factors associated with increased risk of complications after PRB. Results: The median age was 56 (42–68) years old, the majority were male (64%) and white (82%). Ten glomeruli were present in 63.5% of PRBs. Overall, the rate of complications was 16.6%, where 15.1% of them were minor complications and 1.5% were major complications. Perinephritic hematoma accounted for the minor complication that occurred most frequently, whereas the need of a blood transfusion was the prevalent for major complications. By multivariate analysis, increased activated partial thromboplastin time (aPTT; OR 1.11, 95% CI 1.035–1.180) and prebiopsy lower hemoglobin (Hgb; OR 1.61, 95% CI 1.086–2.304) were identified as independent risk factors for major complications. In addition, older patients (OR 1.057, 95% CI 1.001–1.117) were identified as an independent risk factor for blood transfusion requirement. Conclusion: The current risk of complications after native PRB is low. Major complications are most common in case of increased aPTT and decreased Hgb baseline level. |
| first_indexed | 2024-12-11T07:14:36Z |
| format | Article |
| id | doaj.art-38d4b55a956f4e96aa161dee55ab3493 |
| institution | Directory Open Access Journal |
| issn | 1420-4096 1423-0143 |
| language | English |
| last_indexed | 2024-12-11T07:14:36Z |
| publishDate | 2019-12-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Kidney & Blood Pressure Research |
| spelling | doaj.art-38d4b55a956f4e96aa161dee55ab34932022-12-22T01:16:16ZengKarger PublishersKidney & Blood Pressure Research1420-40961423-01432019-12-011910.1159/000504544504544Risk Factors Associated with Major Complications after Ultrasound-Guided Percutaneous Renal Biopsy of Native KidneysBeatriz PombasEva RodríguezJuan SánchezAleksandar RadosevicJavier GimenoMarcos BustoClara BarriosLaia SansJulio PascualMaría José SolerIntroduction: Percutaneous renal biopsy (PRB) of native kidneys is an important tool for diagnosis and management of renal disease. In this study, we analyzed the success, safety, and risk complications of PRB in our center. Methods: A retrospective review of ultrasound-guided PRB done at our institution from January 1998 to December 2017 was performed. Clinical and laboratory data were collected for 661 PRBs. Statistical analysis was performed using the Mann-Whitney U test for continuous variable and chi-square test for categorical variables. Multivariate analysis using logistic regression was performed to assess factors associated with increased risk of complications after PRB. Results: The median age was 56 (42–68) years old, the majority were male (64%) and white (82%). Ten glomeruli were present in 63.5% of PRBs. Overall, the rate of complications was 16.6%, where 15.1% of them were minor complications and 1.5% were major complications. Perinephritic hematoma accounted for the minor complication that occurred most frequently, whereas the need of a blood transfusion was the prevalent for major complications. By multivariate analysis, increased activated partial thromboplastin time (aPTT; OR 1.11, 95% CI 1.035–1.180) and prebiopsy lower hemoglobin (Hgb; OR 1.61, 95% CI 1.086–2.304) were identified as independent risk factors for major complications. In addition, older patients (OR 1.057, 95% CI 1.001–1.117) were identified as an independent risk factor for blood transfusion requirement. Conclusion: The current risk of complications after native PRB is low. Major complications are most common in case of increased aPTT and decreased Hgb baseline level.https://www.karger.com/Article/FullText/504544renal biopsycomplications riskkidney diseasebleeding |
| spellingShingle | Beatriz Pombas Eva Rodríguez Juan Sánchez Aleksandar Radosevic Javier Gimeno Marcos Busto Clara Barrios Laia Sans Julio Pascual María José Soler Risk Factors Associated with Major Complications after Ultrasound-Guided Percutaneous Renal Biopsy of Native Kidneys Kidney & Blood Pressure Research renal biopsy complications risk kidney disease bleeding |
| title | Risk Factors Associated with Major Complications after Ultrasound-Guided Percutaneous Renal Biopsy of Native Kidneys |
| title_full | Risk Factors Associated with Major Complications after Ultrasound-Guided Percutaneous Renal Biopsy of Native Kidneys |
| title_fullStr | Risk Factors Associated with Major Complications after Ultrasound-Guided Percutaneous Renal Biopsy of Native Kidneys |
| title_full_unstemmed | Risk Factors Associated with Major Complications after Ultrasound-Guided Percutaneous Renal Biopsy of Native Kidneys |
| title_short | Risk Factors Associated with Major Complications after Ultrasound-Guided Percutaneous Renal Biopsy of Native Kidneys |
| title_sort | risk factors associated with major complications after ultrasound guided percutaneous renal biopsy of native kidneys |
| topic | renal biopsy complications risk kidney disease bleeding |
| url | https://www.karger.com/Article/FullText/504544 |
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