Aromatic Bromination Abolishes Deficits in Visuospatial Learning Induced by MDMA (“Ecstasy”) in Rats While Preserving the Ability to Increase LTP in the Prefrontal Cortex

Aromatic Bromination Abolishes Deficits in Visuospatial Learning Induced by MDMA (“Ecstasy”) in Rats While Preserving the Ability to Increase LTP in the Prefrontal Cortex

It has recently been demonstrated that aromatic bromination at C(2) abolishes all typical psychomotor, and some key prosocial effects of the entactogen MDMA in rats. Nevertheless, the influence of aromatic bromination on MDMA-like effects on higher cognitive functions remains unexplored. In the pres...

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Bibliographic Details
Main Authors: Patricio Sáez-Briones, Boris Palma, Héctor Burgos, Rafael Barra, Alejandro Hernández
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
MDMA (3,4-methylenedioxymethamphetamine)
2-Br-4,5-MDMA
visuospatial learning
long-term potentiation
prefrontal cortex
Online Access:https://www.mdpi.com/1422-0067/24/4/3724

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