Evaluating the Bioactivity of a Novel Antimicrobial and Anticancer Peptide, Dermaseptin-PS4(Der-PS4), from the Skin Secretion of <i>Phyllomedusa sauvagii</i>

Evaluating the Bioactivity of a Novel Antimicrobial and Anticancer Peptide, Dermaseptin-PS4(Der-PS4), from the Skin Secretion of <i>Phyllomedusa sauvagii</i>

Dermaseptins belonging to a large family of cationic membrane-disruption antimicrobial peptides display extensive antibacterial and antiproliferative activities depending on a coil-to-helix transition and the specific structural parameters. Herein, a novel dermaseptin peptide named Der-PS4 was disco...

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Bibliographic Details
Main Authors: Dong Chen, Xiaowei Zhou, Xi Chen, Linyuan Huang, Xinping Xi, Chengbang Ma, Mei Zhou, Lei Wang, Tianbao Chen
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Molecules
Subjects:
dermaseptin
molecular cloning
antimicrobial peptide
anticancer peptide
frog skin secretion
Online Access:https://www.mdpi.com/1420-3049/24/16/2974

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