Identification of Plasmatic Biomarkers of Foie Gras Qualities in Duck by Metabolomics
The foie gras is an emblematic product of French gastronomy composed of waterfowl fatty liver. The organoleptic qualities of this product depend on the liver characteristics such as liver weight (LW) and technological yield (TY) at cooking. One of the main issues for producers is to classify the foi...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2021-02-01
|
| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2021.628264/full |
| _version_ | 1831525625348751360 |
|---|---|
| author | Zohre Mozduri Zohre Mozduri Nathalie Marty-Gasset Bara Lo Ali Akbar Masoudi Mireille Morisson Cécile Canlet Cécile Canlet Julien Arroyo Agnès Bonnet Cécile M. D. Bonnefont |
| author_facet | Zohre Mozduri Zohre Mozduri Nathalie Marty-Gasset Bara Lo Ali Akbar Masoudi Mireille Morisson Cécile Canlet Cécile Canlet Julien Arroyo Agnès Bonnet Cécile M. D. Bonnefont |
| author_sort | Zohre Mozduri |
| collection | DOAJ |
| description | The foie gras is an emblematic product of French gastronomy composed of waterfowl fatty liver. The organoleptic qualities of this product depend on the liver characteristics such as liver weight (LW) and technological yield (TY) at cooking. One of the main issues for producers is to classify the foie gras with high or low technological quality before cooking them. Thus the study aims at identifying biomarkers of these characteristics with non-invasive biomarkers in duck. 1H-NMR (nuclear magnetic resonance of the proton) analyses were performed on plasma of male mule ducks at different time points during the overfeeding period to obtain a large range of liver characteristics so as to identify plasmatic biomarkers of foie gras. We used two methods, one based on bucket data from the 1H-NMR spectra and another one based on the fingerprints of several metabolites. PLS analyses and Linear models were performed to identify biomarkers. We identified 18 biomarkers of liver weight and 15 biomarkers of technological yield. As these two quality parameters were strongly correlated (−0.82), 13 biomarkers were common. The lactate was the most important biomarker, the other were mainly amino acids. Contrary to the amino acids, the lactate increased with the liver weight and decreased with the technological yield. We also identified 5 biomarkers specific to LW (3 carbohydrates: glucuronic acid, mannose, sorbitol and 2 amino acids: glutamic acid and methionine) that were negatively correlated to liver weight. It was of main interest to identify 2 biomarkers specific to the technological yield. Contrary to the isovaleric acid, the valine was negatively correlated to the technological yield. |
| first_indexed | 2024-12-16T15:54:28Z |
| format | Article |
| id | doaj.art-38d9d35829624465b41bf0e146cbbe58 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-12-16T15:54:28Z |
| publishDate | 2021-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-38d9d35829624465b41bf0e146cbbe582022-12-21T22:25:37ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2021-02-011210.3389/fphys.2021.628264628264Identification of Plasmatic Biomarkers of Foie Gras Qualities in Duck by MetabolomicsZohre Mozduri0Zohre Mozduri1Nathalie Marty-Gasset2Bara Lo3Ali Akbar Masoudi4Mireille Morisson5Cécile Canlet6Cécile Canlet7Julien Arroyo8Agnès Bonnet9Cécile M. D. Bonnefont10GenPhySE, Université de Toulouse, INRAE, ENVT, Castanet Tolosan, FranceDepartment of Animal Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, IranGenPhySE, Université de Toulouse, INRAE, ENVT, Castanet Tolosan, FranceGenPhySE, Université de Toulouse, INRAE, ENVT, Castanet Tolosan, FranceDepartment of Animal Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, IranGenPhySE, Université de Toulouse, INRAE, ENVT, Castanet Tolosan, FranceToxalim, Université de Toulouse, INRA, ENVT, INP-Purpan, UPS, Toulouse, FranceAxiom Platform, MetaToul-MetaboHUB, National Infrastructure for Metabolomics and Fluxomics, Toulouse, FranceASSELDOR, Station d’expérimentation appliquée et de démonstration sur l’oie et le canard, La Tour de Glane, Coulaures, FranceGenPhySE, Université de Toulouse, INRAE, ENVT, Castanet Tolosan, FranceGenPhySE, Université de Toulouse, INRAE, ENVT, Castanet Tolosan, FranceThe foie gras is an emblematic product of French gastronomy composed of waterfowl fatty liver. The organoleptic qualities of this product depend on the liver characteristics such as liver weight (LW) and technological yield (TY) at cooking. One of the main issues for producers is to classify the foie gras with high or low technological quality before cooking them. Thus the study aims at identifying biomarkers of these characteristics with non-invasive biomarkers in duck. 1H-NMR (nuclear magnetic resonance of the proton) analyses were performed on plasma of male mule ducks at different time points during the overfeeding period to obtain a large range of liver characteristics so as to identify plasmatic biomarkers of foie gras. We used two methods, one based on bucket data from the 1H-NMR spectra and another one based on the fingerprints of several metabolites. PLS analyses and Linear models were performed to identify biomarkers. We identified 18 biomarkers of liver weight and 15 biomarkers of technological yield. As these two quality parameters were strongly correlated (−0.82), 13 biomarkers were common. The lactate was the most important biomarker, the other were mainly amino acids. Contrary to the amino acids, the lactate increased with the liver weight and decreased with the technological yield. We also identified 5 biomarkers specific to LW (3 carbohydrates: glucuronic acid, mannose, sorbitol and 2 amino acids: glutamic acid and methionine) that were negatively correlated to liver weight. It was of main interest to identify 2 biomarkers specific to the technological yield. Contrary to the isovaleric acid, the valine was negatively correlated to the technological yield.https://www.frontiersin.org/articles/10.3389/fphys.2021.628264/fullliverfoie grasqualitybiomarkerplasmametabolomics |
| spellingShingle | Zohre Mozduri Zohre Mozduri Nathalie Marty-Gasset Bara Lo Ali Akbar Masoudi Mireille Morisson Cécile Canlet Cécile Canlet Julien Arroyo Agnès Bonnet Cécile M. D. Bonnefont Identification of Plasmatic Biomarkers of Foie Gras Qualities in Duck by Metabolomics Frontiers in Physiology liver foie gras quality biomarker plasma metabolomics |
| title | Identification of Plasmatic Biomarkers of Foie Gras Qualities in Duck by Metabolomics |
| title_full | Identification of Plasmatic Biomarkers of Foie Gras Qualities in Duck by Metabolomics |
| title_fullStr | Identification of Plasmatic Biomarkers of Foie Gras Qualities in Duck by Metabolomics |
| title_full_unstemmed | Identification of Plasmatic Biomarkers of Foie Gras Qualities in Duck by Metabolomics |
| title_short | Identification of Plasmatic Biomarkers of Foie Gras Qualities in Duck by Metabolomics |
| title_sort | identification of plasmatic biomarkers of foie gras qualities in duck by metabolomics |
| topic | liver foie gras quality biomarker plasma metabolomics |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2021.628264/full |
| work_keys_str_mv | AT zohremozduri identificationofplasmaticbiomarkersoffoiegrasqualitiesinduckbymetabolomics AT zohremozduri identificationofplasmaticbiomarkersoffoiegrasqualitiesinduckbymetabolomics AT nathaliemartygasset identificationofplasmaticbiomarkersoffoiegrasqualitiesinduckbymetabolomics AT baralo identificationofplasmaticbiomarkersoffoiegrasqualitiesinduckbymetabolomics AT aliakbarmasoudi identificationofplasmaticbiomarkersoffoiegrasqualitiesinduckbymetabolomics AT mireillemorisson identificationofplasmaticbiomarkersoffoiegrasqualitiesinduckbymetabolomics AT cecilecanlet identificationofplasmaticbiomarkersoffoiegrasqualitiesinduckbymetabolomics AT cecilecanlet identificationofplasmaticbiomarkersoffoiegrasqualitiesinduckbymetabolomics AT julienarroyo identificationofplasmaticbiomarkersoffoiegrasqualitiesinduckbymetabolomics AT agnesbonnet identificationofplasmaticbiomarkersoffoiegrasqualitiesinduckbymetabolomics AT cecilemdbonnefont identificationofplasmaticbiomarkersoffoiegrasqualitiesinduckbymetabolomics |