Exercise-induced increases of corticosterone contribute to exercise-enhanced adult hippocampal neurogenesis in mice

Exercise-induced increases of corticosterone contribute to exercise-enhanced adult hippocampal neurogenesis in mice

Adult hippocampal neurogenesis (AHN) is suppressed by chronic stress. The negative effect of stress is mainly attributed to increased levels of stress hormones (e.g. glucocorticoids, GCs). Exercise enhances AHN, yet it also stimulates GC secretion. To delineate the paradoxical role of GCs, we took t...

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Bibliographic Details
Main Authors: Tzu-Feng Wang, Sheng-Feng Tsai, Zi-Wei Zhao, Monica Meng-Chun Shih, Chia-Yih Wang, Ting-Ting Yang, Yu-Min Kuo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Chinese Journal of Physiology
Subjects:
adult hippocampal neurogenesis
corticosterone
exercise
glucocorticoids
stress
Online Access:http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2021;volume=64;issue=4;spage=186;epage=193;aulast=Wang

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