Dimethylarginine dimethylaminohydrolase 1 protects PM2.5 exposure-induced lung injury in mice by repressing inflammation and oxidative stress

Dimethylarginine dimethylaminohydrolase 1 protects PM2.5 exposure-induced lung injury in mice by repressing inflammation and oxidative stress

Abstract Background Airborne fine particulate matter with aerodynamic diameter ≤ 2.5 μm (PM2.5) pollution is associated with the prevalence of respiratory diseases, including asthma, bronchitis and chronic obstructive pulmonary disease. In patients with those diseases, circulating asymmetric dimethy...

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Bibliographic Details
Main Authors: Junling Gao, Tong Lei, Hongyun Wang, Kai Luo, Yuanli Wang, Bingqing Cui, Zhuoran Yu, Xiaoqi Hu, Fang Zhang, Yingjie Chen, Wenjun Ding, Zhongbing Lu
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Particle and Fibre Toxicology
Subjects:
DDAH1
PM2.5
Lung injury
Inflammation
Oxidative stress
Online Access:https://doi.org/10.1186/s12989-022-00505-7

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