The Effect of Doxycycline on PMA-Induced MUC5B Expression via MMP-9 and p38 in NCI-H292 Cells

The Effect of Doxycycline on PMA-Induced MUC5B Expression via MMP-9 and p38 in NCI-H292 Cells

ObjectivesDoxycycline is commonly used in medicine for its bacteriostatic antimicrobial properties. Recent studies have reported that doxycycline also has anti-inflammatory effects. Matrix metalloproteinase (MMP)-9 has been found to be involved in the physiological and pathological process of inflam...

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Bibliographic Details
Main Authors: Chang Hoon Bae, Seung Min Chen, Heung-Man Lee, Si-Youn Song, Yong-Dae Kim
Format: Article
Language:English
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2011-12-01
Series:Clinical and Experimental Otorhinolaryngology
Subjects:
Doxycycline
Inflammation
Phorbol myristate acetate
Matrix metalloproteinase-9
p38
Mucins
MUC5B
Epithelial cells
NCI-H292 cell
Online Access:http://www.e-ceo.org/upload/pdf/ceo-4-177.pdf

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