Influence of hypoxia on retinal progenitor and ganglion cells in human induced pluripotent stem cell-derived retinal organoids

Influence of hypoxia on retinal progenitor and ganglion cells in human induced pluripotent stem cell-derived retinal organoids

AIM: To observe the effect of low oxygen concentration on the neural retina in human induced pluripotent stem cell (hiPSC)-derived retinal organoids (ROs). METHODS: The hiPSC and a three-dimensional culture method were used for the experiments. Generated embryoid bodies (EBs) were randomly and equal...

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Bibliographic Details
Main Authors: Jin-Lin Du, Li-Xiong Gao, Tao Wang, Zi Ye, Hong-Yu Li, Wen Li, Quan Zeng, Jia-Fei Xi, Wen Yue, Zhao-Hui Li
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2023-10-01
Series:International Journal of Ophthalmology
Subjects:
hypoxia
retinal organoid
retinal progenitor cells
retinal ganglion cells
Online Access:http://ies.ijo.cn/en_publish/2023/10/20231003.pdf

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