Therapeutic effect of a MUC1-specific monoclonal antibody-drug conjugates against pancreatic cancer model

Therapeutic effect of a MUC1-specific monoclonal antibody-drug conjugates against pancreatic cancer model

Abstract Background Pancreatic cancer is one of the most aggressive malignancies without effective targeted therapies. MUC1 has emerged as a potential common target for cancer therapy because it is overexpressed in a variety of different cancers including the majority of pancreatic cancer. However,...

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Bibliographic Details
Main Authors: Guang Wu, Lan Li, Mengnan Liu, Chunyan Chen, Guangze Wang, Zewei Jiang, Yaqian Qin, Licai He, Hongzhi Li, Jiawei Cao, Haihua Gu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cancer Cell International
Subjects:
Mucin1
Humanized monoclonal antibody
Antibody-drug conjugate
MMAE
Pancreatic cancer
Online Access:https://doi.org/10.1186/s12935-022-02839-w

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