Atomic mutagenesis in ion channels with engineered stoichiometry
C-type inactivation of potassium channels fine-tunes the electrical signaling in excitable cells through an internal timing mechanism that is mediated by a hydrogen bond network in the channels' selectively filter. Previously, we used nonsense suppression to highlight the role of the conserved...
Main Authors: | John D Lueck, Adam L Mackey, Daniel T Infield, Jason D Galpin, Jing Li, Benoît Roux, Christopher A Ahern |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/18976 |
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