Single Amino Acid Mutations Affect Zika Virus Replication In Vitro and Virulence In Vivo

Single Amino Acid Mutations Affect Zika Virus Replication In Vitro and Virulence In Vivo

The 2014–2016 Zika virus (ZIKV) epidemic in the Americas resulted in large deposits of next-generation sequencing data from clinical samples. This resource was mined to identify emerging mutations and trends in mutations as the outbreak progressed over time. Information on transmission dynamics, pre...

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Bibliographic Details
Main Authors: Nicole M. Collette, Victoria H. I. Lao, Dina R. Weilhammer, Barbara Zingg, Shoshana D. Cohen, Mona Hwang, Lark L. Coffey, Sarah L. Grady, Adam T. Zemla, Monica K. Borucki
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Viruses
Subjects:
Zika virus
mutation
variant
A129 mouse model
microcephaly
infectious clone
Online Access:https://www.mdpi.com/1999-4915/12/11/1295

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https://www.mdpi.com/1999-4915/12/11/1295

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