Parasites and cancer: A review of the emergence of protozoan carcinogenesis and novel molecular insights.
The role of infectious agents in the formation of cancers has been long established. However the bulk of the emphasis has been on oncogenic DNA viruses and to a lesser extent,bacteria. However,amidst parasites,only a few metazoans have been linked to cancer,and with feeble molecular bases. This revi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Nigerian Journal of Medicine |
| Subjects: | |
| Online Access: | http://www.njmonline.org/article.asp?issn=1115-2613;year=2017;volume=26;issue=1;spage=82;epage=88;aulast=Ajetunmobi;type=0 |
| _version_ | 1818639715379707904 |
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| author | O I Ajetunmobi K I Onyedibe I Emmanuel |
| author_facet | O I Ajetunmobi K I Onyedibe I Emmanuel |
| author_sort | O I Ajetunmobi |
| collection | DOAJ |
| description | The role of infectious agents in the formation of cancers has been long established. However the bulk of the emphasis has been on oncogenic DNA viruses and to a lesser extent,bacteria. However,amidst parasites,only a few metazoans have been linked to cancer,and with feeble molecular bases. This review explores the role of protozoa in cancer formation and highlights new insights into the process of oncogenesis by previously identified helminths with carcinogenic potential. It expounds on the impact of parasites on aspects of cell growth and function, particularly apoptosis,gene expression and cell proliferation. |
| first_indexed | 2024-12-16T22:59:47Z |
| format | Article |
| id | doaj.art-38f80005071744a28450987887474d38 |
| institution | Directory Open Access Journal |
| issn | 1115-2613 |
| language | English |
| last_indexed | 2024-12-16T22:59:47Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Nigerian Journal of Medicine |
| spelling | doaj.art-38f80005071744a28450987887474d382022-12-21T22:12:45ZengWolters Kluwer Medknow PublicationsNigerian Journal of Medicine1115-26132017-01-01261828810.4103/1115-2613.278838Parasites and cancer: A review of the emergence of protozoan carcinogenesis and novel molecular insights.O I AjetunmobiK I OnyedibeI EmmanuelThe role of infectious agents in the formation of cancers has been long established. However the bulk of the emphasis has been on oncogenic DNA viruses and to a lesser extent,bacteria. However,amidst parasites,only a few metazoans have been linked to cancer,and with feeble molecular bases. This review explores the role of protozoa in cancer formation and highlights new insights into the process of oncogenesis by previously identified helminths with carcinogenic potential. It expounds on the impact of parasites on aspects of cell growth and function, particularly apoptosis,gene expression and cell proliferation.http://www.njmonline.org/article.asp?issn=1115-2613;year=2017;volume=26;issue=1;spage=82;epage=88;aulast=Ajetunmobi;type=0protozoacanceroncogenesishelminthsapoptosis |
| spellingShingle | O I Ajetunmobi K I Onyedibe I Emmanuel Parasites and cancer: A review of the emergence of protozoan carcinogenesis and novel molecular insights. Nigerian Journal of Medicine protozoa cancer oncogenesis helminths apoptosis |
| title | Parasites and cancer: A review of the emergence of protozoan carcinogenesis and novel molecular insights. |
| title_full | Parasites and cancer: A review of the emergence of protozoan carcinogenesis and novel molecular insights. |
| title_fullStr | Parasites and cancer: A review of the emergence of protozoan carcinogenesis and novel molecular insights. |
| title_full_unstemmed | Parasites and cancer: A review of the emergence of protozoan carcinogenesis and novel molecular insights. |
| title_short | Parasites and cancer: A review of the emergence of protozoan carcinogenesis and novel molecular insights. |
| title_sort | parasites and cancer a review of the emergence of protozoan carcinogenesis and novel molecular insights |
| topic | protozoa cancer oncogenesis helminths apoptosis |
| url | http://www.njmonline.org/article.asp?issn=1115-2613;year=2017;volume=26;issue=1;spage=82;epage=88;aulast=Ajetunmobi;type=0 |
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