Synthetic lethality-based prediction of anti-SARS-CoV-2 targets

Synthetic lethality-based prediction of anti-SARS-CoV-2 targets

Summary: Novel strategies are needed to identify drug targets and treatments for the COVID-19 pandemic. The altered gene expression of virus-infected host cells provides an opportunity to specifically inhibit viral propagation via targeting the synthetic lethal and synthetic dosage lethal (SL/SDL) p...

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Bibliographic Details
Main Authors: Lipika R. Pal, Kuoyuan Cheng, Nishanth Ulhas Nair, Laura Martin-Sancho, Sanju Sinha, Yuan Pu, Laura Riva, Xin Yin, Fiorella Schischlik, Joo Sang Lee, Sumit K. Chanda, Eytan Ruppin
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:iScience
Subjects:
Drugs
Virology
Synthetic biology
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422200582X

Internet

http://www.sciencedirect.com/science/article/pii/S258900422200582X

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