Towards the Application of a Label-Free Approach for Anti-CD47/PD-L1 Bispecific Antibody Discovery

Towards the Application of a Label-Free Approach for Anti-CD47/PD-L1 Bispecific Antibody Discovery

The engineering of bispecific antibodies that exhibit optimal affinity and functional activity presents a significant scientific challenge. To tackle this, investigators employ an assortment of protein assay techniques, such as label-free interaction methodologies, which offer rapidity and convenien...

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Bibliographic Details
Main Authors: Artem S. Grevtsev, Alexandra D. Azarian, Alexey K. Misorin, Daria O. Chernyshova, Pavel A. Iakovlev, Mikhail S. Karbyshev
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biosensors
Subjects:
antibodies
bispecific antibodies
label-free
BLI
CD47
PD-L1
Online Access:https://www.mdpi.com/2079-6374/13/12/1022

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