Risk Factors for Post-Stroke Pneumonia in a Patient Population with Subacute Stroke: A Retrospective Cohort Study
The risk of pneumonia and death is higher in acute stroke patients with signs of pulmonary infection on chest computed tomography (CT) at admission. However, few reports have examined the incidence of pneumonia and its predictors in subacute stroke patients. The aim of this study was to examine fact...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-09-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/12/18/5835 |
| _version_ | 1797579497307897856 |
|---|---|
| author | Hiroyuki Tashima Mari Ito Michiyuki Kawakami Ryota Ishii Yuta Miyazaki Tomonori Akimoto Masahiro Tsujikawa Keigo Kobayashi Kunitsugu Kondo Tetsuya Tsuji |
| author_facet | Hiroyuki Tashima Mari Ito Michiyuki Kawakami Ryota Ishii Yuta Miyazaki Tomonori Akimoto Masahiro Tsujikawa Keigo Kobayashi Kunitsugu Kondo Tetsuya Tsuji |
| author_sort | Hiroyuki Tashima |
| collection | DOAJ |
| description | The risk of pneumonia and death is higher in acute stroke patients with signs of pulmonary infection on chest computed tomography (CT) at admission. However, few reports have examined the incidence of pneumonia and its predictors in subacute stroke patients. The aim of this study was to examine factors related to post-stroke pneumonia in subacute stroke patients. A total of 340 subacute stroke patients were included. Univariable logistic regression analysis was performed using variables that may contribute to pneumonia, with the development of pneumonia as the dependent variable. Multivariable logistic regression analysis using the three independent variables with the lowest <i>p</i>-values on the univariable logistic regression analysis was also performed to calculate adjusted odds ratios. Twenty-two patients developed pneumonia during hospitalization. The univariable logistic regression analysis showed that the top three items were serum albumin (Alb), functional Oral Intake Scale (FOIS) score, and signs of pulmonary infection on chest CT at admission. Multivariable logistic regression analysis adjusted for these three items showed that the presence of signs of pulmonary infection on chest CT at admission was the independent variable (OR: 4.45; 95% CI: 1.54–12.9). When signs of pulmonary infection are seen on admission chest CT, careful follow-up is necessary because pneumonia is significantly more likely to occur during hospitalization. |
| first_indexed | 2024-03-10T22:37:02Z |
| format | Article |
| id | doaj.art-38fd5c5c65a04b7ba31adce9a8d9da4b |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T22:37:02Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-38fd5c5c65a04b7ba31adce9a8d9da4b2023-11-19T11:18:02ZengMDPI AGJournal of Clinical Medicine2077-03832023-09-011218583510.3390/jcm12185835Risk Factors for Post-Stroke Pneumonia in a Patient Population with Subacute Stroke: A Retrospective Cohort StudyHiroyuki Tashima0Mari Ito1Michiyuki Kawakami2Ryota Ishii3Yuta Miyazaki4Tomonori Akimoto5Masahiro Tsujikawa6Keigo Kobayashi7Kunitsugu Kondo8Tetsuya Tsuji9Department of Rehabilitation Medicine, Tokyo Bay Rehabilitation Hospital, Chiba 275-0026, JapanDepartment of Rehabilitation Medicine, Tokyo Bay Rehabilitation Hospital, Chiba 275-0026, JapanDepartment of Rehabilitation Medicine, Tokyo Bay Rehabilitation Hospital, Chiba 275-0026, JapanDepartment of Biostatistics, Faculty of Medicine, University of Tsukuba, Ibaraki 305-8577, JapanDepartment of Rehabilitation Medicine, Tokyo Bay Rehabilitation Hospital, Chiba 275-0026, JapanDepartment of Rehabilitation Medicine, Tokyo Bay Rehabilitation Hospital, Chiba 275-0026, JapanDepartment of Rehabilitation Medicine, Tokyo Bay Rehabilitation Hospital, Chiba 275-0026, JapanDepartment of Radiology, Yatsu Hoken Hospital, Chiba 275-0026, JapanDepartment of Rehabilitation Medicine, Tokyo Bay Rehabilitation Hospital, Chiba 275-0026, JapanDepartment of Rehabilitation Medicine, Keio University School of Medicine, Tokyo 160-8582, JapanThe risk of pneumonia and death is higher in acute stroke patients with signs of pulmonary infection on chest computed tomography (CT) at admission. However, few reports have examined the incidence of pneumonia and its predictors in subacute stroke patients. The aim of this study was to examine factors related to post-stroke pneumonia in subacute stroke patients. A total of 340 subacute stroke patients were included. Univariable logistic regression analysis was performed using variables that may contribute to pneumonia, with the development of pneumonia as the dependent variable. Multivariable logistic regression analysis using the three independent variables with the lowest <i>p</i>-values on the univariable logistic regression analysis was also performed to calculate adjusted odds ratios. Twenty-two patients developed pneumonia during hospitalization. The univariable logistic regression analysis showed that the top three items were serum albumin (Alb), functional Oral Intake Scale (FOIS) score, and signs of pulmonary infection on chest CT at admission. Multivariable logistic regression analysis adjusted for these three items showed that the presence of signs of pulmonary infection on chest CT at admission was the independent variable (OR: 4.45; 95% CI: 1.54–12.9). When signs of pulmonary infection are seen on admission chest CT, careful follow-up is necessary because pneumonia is significantly more likely to occur during hospitalization.https://www.mdpi.com/2077-0383/12/18/5835subacute strokepost-stroke pneumoniarehabilitationpredictorscomprehensive rehabilitation ward |
| spellingShingle | Hiroyuki Tashima Mari Ito Michiyuki Kawakami Ryota Ishii Yuta Miyazaki Tomonori Akimoto Masahiro Tsujikawa Keigo Kobayashi Kunitsugu Kondo Tetsuya Tsuji Risk Factors for Post-Stroke Pneumonia in a Patient Population with Subacute Stroke: A Retrospective Cohort Study Journal of Clinical Medicine subacute stroke post-stroke pneumonia rehabilitation predictors comprehensive rehabilitation ward |
| title | Risk Factors for Post-Stroke Pneumonia in a Patient Population with Subacute Stroke: A Retrospective Cohort Study |
| title_full | Risk Factors for Post-Stroke Pneumonia in a Patient Population with Subacute Stroke: A Retrospective Cohort Study |
| title_fullStr | Risk Factors for Post-Stroke Pneumonia in a Patient Population with Subacute Stroke: A Retrospective Cohort Study |
| title_full_unstemmed | Risk Factors for Post-Stroke Pneumonia in a Patient Population with Subacute Stroke: A Retrospective Cohort Study |
| title_short | Risk Factors for Post-Stroke Pneumonia in a Patient Population with Subacute Stroke: A Retrospective Cohort Study |
| title_sort | risk factors for post stroke pneumonia in a patient population with subacute stroke a retrospective cohort study |
| topic | subacute stroke post-stroke pneumonia rehabilitation predictors comprehensive rehabilitation ward |
| url | https://www.mdpi.com/2077-0383/12/18/5835 |
| work_keys_str_mv | AT hiroyukitashima riskfactorsforpoststrokepneumoniainapatientpopulationwithsubacutestrokearetrospectivecohortstudy AT mariito riskfactorsforpoststrokepneumoniainapatientpopulationwithsubacutestrokearetrospectivecohortstudy AT michiyukikawakami riskfactorsforpoststrokepneumoniainapatientpopulationwithsubacutestrokearetrospectivecohortstudy AT ryotaishii riskfactorsforpoststrokepneumoniainapatientpopulationwithsubacutestrokearetrospectivecohortstudy AT yutamiyazaki riskfactorsforpoststrokepneumoniainapatientpopulationwithsubacutestrokearetrospectivecohortstudy AT tomonoriakimoto riskfactorsforpoststrokepneumoniainapatientpopulationwithsubacutestrokearetrospectivecohortstudy AT masahirotsujikawa riskfactorsforpoststrokepneumoniainapatientpopulationwithsubacutestrokearetrospectivecohortstudy AT keigokobayashi riskfactorsforpoststrokepneumoniainapatientpopulationwithsubacutestrokearetrospectivecohortstudy AT kunitsugukondo riskfactorsforpoststrokepneumoniainapatientpopulationwithsubacutestrokearetrospectivecohortstudy AT tetsuyatsuji riskfactorsforpoststrokepneumoniainapatientpopulationwithsubacutestrokearetrospectivecohortstudy |