Cannabinoid Receptor Agonist WIN55, 212-2 Attenuates Injury in the Hippocampus of Rats after Deep Hypothermic Circulatory Arrest

Cannabinoid Receptor Agonist WIN55, 212-2 Attenuates Injury in the Hippocampus of Rats after Deep Hypothermic Circulatory Arrest

Objectives: Postoperative neurological deficits remain a challenge in cardiac surgery employing deep hypothermic circulatory arrest (DHCA). This study aimed to investigate the effect of WIN55, 212-2, a cannabinoid agonist, on brain injury in a rat model of DHCA. Methods: Twenty-four male Sprague Daw...

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Bibliographic Details
Main Authors: Ming-Huan Yu, Qin Yang, You-Peng Zhang, Jia-Hui Wang, Ren-Jian-Zhi Zhang, Zhi-Gang Liu, Xiao-Cheng Liu
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Brain Sciences
Subjects:
deep hypothermic circulatory arrest
cannabinoid receptor
neuroprotection
Online Access:https://www.mdpi.com/2076-3425/13/3/525

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https://www.mdpi.com/2076-3425/13/3/525

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