Hydroxy Chalcones and Analogs with Chemopreventive Properties
The aim of this review is to highlight the chemopreventive properties of hydroxy-substituted natural and synthetic chalcones along with a number of their analogs. These products display various biological activities, and have many applications against various diseases. Antioxidant and anti-inflammat...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/13/10667 |
| _version_ | 1797591541100838912 |
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| author | Mihail Lucian Birsa Laura G. Sarbu |
| author_facet | Mihail Lucian Birsa Laura G. Sarbu |
| author_sort | Mihail Lucian Birsa |
| collection | DOAJ |
| description | The aim of this review is to highlight the chemopreventive properties of hydroxy-substituted natural and synthetic chalcones along with a number of their analogs. These products display various biological activities, and have many applications against various diseases. Antioxidant and anti-inflammatory properties of chalcones bearing hydroxy substituents are underlined. The influence of hydroxy substituents located on ring A, B, or both are systematized according to the exhibited biological properties. |
| first_indexed | 2024-03-11T01:39:51Z |
| format | Article |
| id | doaj.art-3901cc932431493fa7934abd9ad1edd1 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T01:39:51Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-3901cc932431493fa7934abd9ad1edd12023-11-18T16:41:40ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-06-0124131066710.3390/ijms241310667Hydroxy Chalcones and Analogs with Chemopreventive PropertiesMihail Lucian Birsa0Laura G. Sarbu1Department of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I Blvd., 700506 Iasi, RomaniaDepartment of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I Blvd., 700506 Iasi, RomaniaThe aim of this review is to highlight the chemopreventive properties of hydroxy-substituted natural and synthetic chalcones along with a number of their analogs. These products display various biological activities, and have many applications against various diseases. Antioxidant and anti-inflammatory properties of chalcones bearing hydroxy substituents are underlined. The influence of hydroxy substituents located on ring A, B, or both are systematized according to the exhibited biological properties.https://www.mdpi.com/1422-0067/24/13/10667chalconesantioxidantsanti-inflammatorychemopreventive |
| spellingShingle | Mihail Lucian Birsa Laura G. Sarbu Hydroxy Chalcones and Analogs with Chemopreventive Properties International Journal of Molecular Sciences chalcones antioxidants anti-inflammatory chemopreventive |
| title | Hydroxy Chalcones and Analogs with Chemopreventive Properties |
| title_full | Hydroxy Chalcones and Analogs with Chemopreventive Properties |
| title_fullStr | Hydroxy Chalcones and Analogs with Chemopreventive Properties |
| title_full_unstemmed | Hydroxy Chalcones and Analogs with Chemopreventive Properties |
| title_short | Hydroxy Chalcones and Analogs with Chemopreventive Properties |
| title_sort | hydroxy chalcones and analogs with chemopreventive properties |
| topic | chalcones antioxidants anti-inflammatory chemopreventive |
| url | https://www.mdpi.com/1422-0067/24/13/10667 |
| work_keys_str_mv | AT mihaillucianbirsa hydroxychalconesandanalogswithchemopreventiveproperties AT lauragsarbu hydroxychalconesandanalogswithchemopreventiveproperties |