FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization
In this paper we are focused on analysis of hydroxychalcones, i.e. 2’-hydroxychalcone, 3’-hydroxychalcone and 4’-hydroxychalcone, by the Flowing Atmospheric Pressure Afterglow mass spectrometry (FAPA-MS), and on comparison of the obtained data with other classical methods including ESI-MS, APCI, MAL...
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| Format: | Article |
| Language: | English |
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Sciendo
2014-06-01
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| Series: | Current Issues in Pharmacy and Medical Sciences |
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| Online Access: | https://doi.org/10.2478/cipms-2014-0008 |
| _version_ | 1818362534712836096 |
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| author | Smoluch Marek Bartkowiak Grazyna Reszke Edward Lechowicz Wojciech Silberring Jerzy Schroeder Grzegorz |
| author_facet | Smoluch Marek Bartkowiak Grazyna Reszke Edward Lechowicz Wojciech Silberring Jerzy Schroeder Grzegorz |
| author_sort | Smoluch Marek |
| collection | DOAJ |
| description | In this paper we are focused on analysis of hydroxychalcones, i.e. 2’-hydroxychalcone, 3’-hydroxychalcone and 4’-hydroxychalcone, by the Flowing Atmospheric Pressure Afterglow mass spectrometry (FAPA-MS), and on comparison of the obtained data with other classical methods including ESI-MS, APCI, MALDI, and GC/EI-MS. The paper is presenting fragmentation pathways of both positive-, and negative hydroxychalcone ions. Tested compounds were characterized by comparison of the results (signals m/z and relative intensities) from the five mass spectrometry techniques, showing very good utility of FAPA method for fast and easy analysis of the low molecular weight compounds. Moreover, FAPA does not require a time-consuming derivatization, nor search for a suitable solvent or matrix, often incompatible with various ion sources. |
| first_indexed | 2024-12-13T21:34:07Z |
| format | Article |
| id | doaj.art-3905d8c34472464f827025fe6884f94e |
| institution | Directory Open Access Journal |
| issn | 2084-980X 2300-6676 |
| language | English |
| last_indexed | 2024-12-13T21:34:07Z |
| publishDate | 2014-06-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Current Issues in Pharmacy and Medical Sciences |
| spelling | doaj.art-3905d8c34472464f827025fe6884f94e2022-12-21T23:30:43ZengSciendoCurrent Issues in Pharmacy and Medical Sciences2084-980X2300-66762014-06-01271273110.2478/cipms-2014-0008cipms-2014-0008FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionizationSmoluch Marek0Bartkowiak Grazyna1Reszke Edward2Lechowicz Wojciech3Silberring Jerzy4Schroeder Grzegorz5AGH University of Science and Technology, Department of Biochemistry and Neurobiology, Faculty of Materials Science and Ceramics, Mickiewicza 30, 30-059 Cracow, PolandAdam Mickiewicz University in Poznań, Faculty of Chemistry, Umultowska 89b, 61-614 Poznan, PolandERTEC-Poland, Rogowska 146/5, 54-440 Wroclaw, PolandInstitute of Forensic Research, Westerplatte 9, 31-033 Cracow, PolandAGH University of Science and Technology, Department of Biochemistry and Neurobiology, Faculty of Materials Science and Ceramics, Mickiewicza 30, 30-059 Cracow, PolandAdam Mickiewicz University in Poznań, Faculty of Chemistry, Umultowska 89b, 61-614 Poznan, PolandIn this paper we are focused on analysis of hydroxychalcones, i.e. 2’-hydroxychalcone, 3’-hydroxychalcone and 4’-hydroxychalcone, by the Flowing Atmospheric Pressure Afterglow mass spectrometry (FAPA-MS), and on comparison of the obtained data with other classical methods including ESI-MS, APCI, MALDI, and GC/EI-MS. The paper is presenting fragmentation pathways of both positive-, and negative hydroxychalcone ions. Tested compounds were characterized by comparison of the results (signals m/z and relative intensities) from the five mass spectrometry techniques, showing very good utility of FAPA method for fast and easy analysis of the low molecular weight compounds. Moreover, FAPA does not require a time-consuming derivatization, nor search for a suitable solvent or matrix, often incompatible with various ion sources.https://doi.org/10.2478/cipms-2014-0008fapamass spectrometryhydroxychalcones |
| spellingShingle | Smoluch Marek Bartkowiak Grazyna Reszke Edward Lechowicz Wojciech Silberring Jerzy Schroeder Grzegorz FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization Current Issues in Pharmacy and Medical Sciences fapa mass spectrometry hydroxychalcones |
| title | FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization |
| title_full | FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization |
| title_fullStr | FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization |
| title_full_unstemmed | FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization |
| title_short | FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization |
| title_sort | fapa mass spectrometry of hydroxychalcones comparative studies with classical methods of ionization |
| topic | fapa mass spectrometry hydroxychalcones |
| url | https://doi.org/10.2478/cipms-2014-0008 |
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