The role of the L-arginine-NO-cGMP pathway in the development of tolerance to mephedrone-induced hyperlocomotion in mice

The role of the L-arginine-NO-cGMP pathway in the development of tolerance to mephedrone-induced hyperlocomotion in mice

The tendency of a psychostimulant to increase locomotion in rodents is considered to be associated with its addictive properties. Mephedrone, one of the most popular psychoactive substances used recreationally, is known to enhance locomotor activity in mice, but little is known about the potential d...

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Bibliographic Details
Main Authors: Bielecka-Papierz Gabriela, Poleszak Ewa, Szopa Aleksandra, Listos Joanna, Orzelska-Gorka Jolanta, Jakobczuk Małgorzata, Baluk Kamila, Talarek Sylwia, Serefko Anna
Format: Article
Language:English
Published: Sciendo 2023-06-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
mephedrone
l-name
methylene blue
l-arginine hydrochloride
sildenafil citrate
mice
Online Access:https://doi.org/10.2478/cipms-2023-0020

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