P-53 HELICOBACTER PYLORI INFECTION IN PATIENTS WITH PEPTIC ULCER DISEASE AND CIRRHOSIS OF THE LIVER
Introduction and Objectives: An increased rate of peptic ulcer disease (PUD) has been described in patients with cirrhosis. Helicobacter pylori (Hp) infection rates are lower than in the non-cirrhotic population. Peru has a high prevalence of Hp infection, but there is no information on this associa...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-03-01
|
| Series: | Annals of Hepatology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268123000571 |
| _version_ | 1827981877699411968 |
|---|---|
| author | Jaime Fustamante Eduardo Monge Claudia Soto Julio Narroquin Lucero Torres |
| author_facet | Jaime Fustamante Eduardo Monge Claudia Soto Julio Narroquin Lucero Torres |
| author_sort | Jaime Fustamante |
| collection | DOAJ |
| description | Introduction and Objectives: An increased rate of peptic ulcer disease (PUD) has been described in patients with cirrhosis. Helicobacter pylori (Hp) infection rates are lower than in the non-cirrhotic population. Peru has a high prevalence of Hp infection, but there is no information on this association in our population. This study aimed to study the association between PUD and Hp in patients with cirrhosis. Materials and Methods: All patients with an endoscopic diagnosis of PUD between 2014 and 2019 at Daniel Carrion Hospital were reviewed. The frequency of Hp infection in patients with PUD with and without cirrhosis was assessed. Statistical differences were accepted with a p value < 0,05. Results: A total of 574 patients with PUD were included. 72(13%) had cirrhosis. In patients with cirrhosis, Hp was positive in 24 (33%); in those without cirrhosis, Hp was positive in 285 (57%), p <0,05. See table 1. In patients with cirrhosis and PUD and Hp positive, 83% were gastric ulcers. Of those without cirrhosis, 55% were gastric ulcers. Conclusions: There is a lower prevalence of Hp infection in patients with PUD and cirrhosis as compared with no cirrhotic PUD patients. |
| first_indexed | 2024-04-09T22:15:58Z |
| format | Article |
| id | doaj.art-39069d5c42204ca1a977e8c8fbfeefb8 |
| institution | Directory Open Access Journal |
| issn | 1665-2681 |
| language | English |
| last_indexed | 2024-04-09T22:15:58Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Annals of Hepatology |
| spelling | doaj.art-39069d5c42204ca1a977e8c8fbfeefb82023-03-23T04:34:07ZengElsevierAnnals of Hepatology1665-26812023-03-0128100953P-53 HELICOBACTER PYLORI INFECTION IN PATIENTS WITH PEPTIC ULCER DISEASE AND CIRRHOSIS OF THE LIVERJaime Fustamante0Eduardo Monge1Claudia Soto2Julio Narroquin3Lucero Torres4Gastroenterology Service, Nacional Hospital Daniel Alcides Carrión, Callao, Peru; Peruvian University of Applied Sciences Lima, PeruGastroenterology Service, Nacional Hospital Daniel Alcides Carrión, Callao, Peru; Peruvian University of Applied Sciences Lima, PeruGastroenterology Service, Nacional Hospital Daniel Alcides Carrión, Callao, Peru; Peruvian University of Applied Sciences Lima, PeruGastroenterology Service, Nacional Hospital Daniel Alcides Carrión, Callao, Peru; Peruvian University of Applied Sciences Lima, PeruGastroenterology Service, Nacional Hospital Daniel Alcides Carrión, Callao, Peru; Peruvian University of Applied Sciences Lima, PeruIntroduction and Objectives: An increased rate of peptic ulcer disease (PUD) has been described in patients with cirrhosis. Helicobacter pylori (Hp) infection rates are lower than in the non-cirrhotic population. Peru has a high prevalence of Hp infection, but there is no information on this association in our population. This study aimed to study the association between PUD and Hp in patients with cirrhosis. Materials and Methods: All patients with an endoscopic diagnosis of PUD between 2014 and 2019 at Daniel Carrion Hospital were reviewed. The frequency of Hp infection in patients with PUD with and without cirrhosis was assessed. Statistical differences were accepted with a p value < 0,05. Results: A total of 574 patients with PUD were included. 72(13%) had cirrhosis. In patients with cirrhosis, Hp was positive in 24 (33%); in those without cirrhosis, Hp was positive in 285 (57%), p <0,05. See table 1. In patients with cirrhosis and PUD and Hp positive, 83% were gastric ulcers. Of those without cirrhosis, 55% were gastric ulcers. Conclusions: There is a lower prevalence of Hp infection in patients with PUD and cirrhosis as compared with no cirrhotic PUD patients.http://www.sciencedirect.com/science/article/pii/S1665268123000571 |
| spellingShingle | Jaime Fustamante Eduardo Monge Claudia Soto Julio Narroquin Lucero Torres P-53 HELICOBACTER PYLORI INFECTION IN PATIENTS WITH PEPTIC ULCER DISEASE AND CIRRHOSIS OF THE LIVER Annals of Hepatology |
| title | P-53 HELICOBACTER PYLORI INFECTION IN PATIENTS WITH PEPTIC ULCER DISEASE AND CIRRHOSIS OF THE LIVER |
| title_full | P-53 HELICOBACTER PYLORI INFECTION IN PATIENTS WITH PEPTIC ULCER DISEASE AND CIRRHOSIS OF THE LIVER |
| title_fullStr | P-53 HELICOBACTER PYLORI INFECTION IN PATIENTS WITH PEPTIC ULCER DISEASE AND CIRRHOSIS OF THE LIVER |
| title_full_unstemmed | P-53 HELICOBACTER PYLORI INFECTION IN PATIENTS WITH PEPTIC ULCER DISEASE AND CIRRHOSIS OF THE LIVER |
| title_short | P-53 HELICOBACTER PYLORI INFECTION IN PATIENTS WITH PEPTIC ULCER DISEASE AND CIRRHOSIS OF THE LIVER |
| title_sort | p 53 helicobacter pylori infection in patients with peptic ulcer disease and cirrhosis of the liver |
| url | http://www.sciencedirect.com/science/article/pii/S1665268123000571 |
| work_keys_str_mv | AT jaimefustamante p53helicobacterpyloriinfectioninpatientswithpepticulcerdiseaseandcirrhosisoftheliver AT eduardomonge p53helicobacterpyloriinfectioninpatientswithpepticulcerdiseaseandcirrhosisoftheliver AT claudiasoto p53helicobacterpyloriinfectioninpatientswithpepticulcerdiseaseandcirrhosisoftheliver AT julionarroquin p53helicobacterpyloriinfectioninpatientswithpepticulcerdiseaseandcirrhosisoftheliver AT lucerotorres p53helicobacterpyloriinfectioninpatientswithpepticulcerdiseaseandcirrhosisoftheliver |