Fucoidan Extracted From Sporophyll of Undaria pinnatifida Grown in Weihai, China – Chemical Composition and Comparison of Antioxidant Activity of Different Molecular Weight Fractions
Fucoidan is a multifunctional marine carbohydrate polymer that differs in its chemical composition and bioactivity both between seaweed species and within species from different locations across the globe. In this study, fucoidan was extracted from the sporophyll of Undaria pinnatifida grown in Weih...
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Frontiers Media S.A.
2021-05-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2021.636930/full |
| _version_ | 1818938025952935936 |
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| author | Jing Yu Jing Yu Qianqian Li Jun Wu Xiaotong Yang Shiping Yang Wei Zhu Yang Liu Wei Tang Shaoping Nie Amira Hassouna Amira Hassouna William Lindsey White Yu Zhao Jun Lu Jun Lu Jun Lu Jun Lu Jun Lu Jun Lu |
| author_facet | Jing Yu Jing Yu Qianqian Li Jun Wu Xiaotong Yang Shiping Yang Wei Zhu Yang Liu Wei Tang Shaoping Nie Amira Hassouna Amira Hassouna William Lindsey White Yu Zhao Jun Lu Jun Lu Jun Lu Jun Lu Jun Lu Jun Lu |
| author_sort | Jing Yu |
| collection | DOAJ |
| description | Fucoidan is a multifunctional marine carbohydrate polymer that differs in its chemical composition and bioactivity both between seaweed species and within species from different locations across the globe. In this study, fucoidan was extracted from the sporophyll of Undaria pinnatifida grown in Weihai, Shandong Province, China. Fucoidan fractions with molecular weight cutoffs (MWCO) of >300 kDa and <10 kDa were obtained via dialysis. The fucoidan standard from Sigma (Fstd, ≥95, CAS: 9072-19-9), fucoidan crude extract (WH), >300 kDa fraction (300k) and <10 kDa fraction (10k) were compared in terms of chemical composition and antioxidant capacity. Based on Fourier transform infrared spectroscopy (FT-IR) analysis, Fstd, WH, and 300k all showed strong bands around 830 cm−1, corresponding to the sulfate substituent in the molecule. The results showed that compared with WH and 300 k, the degree of sulfation at 10k was the lowest. From Nuclear magnetic resonance spectroscopy (NMR) result, the four fucoidan samples all contain α-L-fucose. The primary antioxidant ability of the 10k is significantly higher than that of the 300k, WH, and Fstd, but the secondary antioxidant capabilities of the 10k and 300k were similar, and both were higher than that of the butylated hydroxyanisole (BHA). The ferric reducing antioxidant ability was higher in the 300k and WH fractions. This demonstrates that fucoidan extracted from U. pinnatifida grown in Weihai, China should be a useful nutraceutical resource. |
| first_indexed | 2024-12-20T06:01:18Z |
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| id | doaj.art-39088e335bf0464c8ba6d85b1a8716ea |
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| issn | 2296-861X |
| language | English |
| last_indexed | 2024-12-20T06:01:18Z |
| publishDate | 2021-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-39088e335bf0464c8ba6d85b1a8716ea2022-12-21T19:50:55ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2021-05-01810.3389/fnut.2021.636930636930Fucoidan Extracted From Sporophyll of Undaria pinnatifida Grown in Weihai, China – Chemical Composition and Comparison of Antioxidant Activity of Different Molecular Weight FractionsJing Yu0Jing Yu1Qianqian Li2Jun Wu3Xiaotong Yang4Shiping Yang5Wei Zhu6Yang Liu7Wei Tang8Shaoping Nie9Amira Hassouna10Amira Hassouna11William Lindsey White12Yu Zhao13Jun Lu14Jun Lu15Jun Lu16Jun Lu17Jun Lu18Jun Lu19College of Life Sciences, Shanghai Normal University, Shanghai, ChinaCollege of Chemistry and Materials Science, Shanghai Normal University, Shanghai, ChinaCollege of Life Sciences, Shanghai Normal University, Shanghai, ChinaCollege of Life Sciences, Shanghai Normal University, Shanghai, ChinaCollege of Life Sciences, Shanghai Normal University, Shanghai, ChinaCollege of Chemistry and Materials Science, Shanghai Normal University, Shanghai, ChinaShanghai Institute of Quality Inspection and Technical Research, Shanghai, ChinaShanghai Institute of Quality Inspection and Technical Research, Shanghai, ChinaState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, ChinaState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, ChinaFaculty of Health and Environmental Sciences, School of Public Health and Interdisciplinary Studies, Auckland University of Technology, Auckland, New ZealandDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Cairo, EgyptSchool of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland, New ZealandCollege of Life Sciences, Shanghai Normal University, Shanghai, ChinaFaculty of Health and Environmental Sciences, School of Public Health and Interdisciplinary Studies, Auckland University of Technology, Auckland, New ZealandSchool of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland, New ZealandInstitute of Biomedical Technology, Auckland University of Technology, Auckland, New ZealandMaurice Wilkins Centre for Molecular Discovery, Auckland, New Zealand0College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China1College of Food Engineering and Nutrition Sciences, Shaanxi Normal University, Shaanxi, ChinaFucoidan is a multifunctional marine carbohydrate polymer that differs in its chemical composition and bioactivity both between seaweed species and within species from different locations across the globe. In this study, fucoidan was extracted from the sporophyll of Undaria pinnatifida grown in Weihai, Shandong Province, China. Fucoidan fractions with molecular weight cutoffs (MWCO) of >300 kDa and <10 kDa were obtained via dialysis. The fucoidan standard from Sigma (Fstd, ≥95, CAS: 9072-19-9), fucoidan crude extract (WH), >300 kDa fraction (300k) and <10 kDa fraction (10k) were compared in terms of chemical composition and antioxidant capacity. Based on Fourier transform infrared spectroscopy (FT-IR) analysis, Fstd, WH, and 300k all showed strong bands around 830 cm−1, corresponding to the sulfate substituent in the molecule. The results showed that compared with WH and 300 k, the degree of sulfation at 10k was the lowest. From Nuclear magnetic resonance spectroscopy (NMR) result, the four fucoidan samples all contain α-L-fucose. The primary antioxidant ability of the 10k is significantly higher than that of the 300k, WH, and Fstd, but the secondary antioxidant capabilities of the 10k and 300k were similar, and both were higher than that of the butylated hydroxyanisole (BHA). The ferric reducing antioxidant ability was higher in the 300k and WH fractions. This demonstrates that fucoidan extracted from U. pinnatifida grown in Weihai, China should be a useful nutraceutical resource.https://www.frontiersin.org/articles/10.3389/fnut.2021.636930/fullfucoidanmolecular weightantioxidantfractionchemical compositionnutraceutical |
| spellingShingle | Jing Yu Jing Yu Qianqian Li Jun Wu Xiaotong Yang Shiping Yang Wei Zhu Yang Liu Wei Tang Shaoping Nie Amira Hassouna Amira Hassouna William Lindsey White Yu Zhao Jun Lu Jun Lu Jun Lu Jun Lu Jun Lu Jun Lu Fucoidan Extracted From Sporophyll of Undaria pinnatifida Grown in Weihai, China – Chemical Composition and Comparison of Antioxidant Activity of Different Molecular Weight Fractions Frontiers in Nutrition fucoidan molecular weight antioxidant fraction chemical composition nutraceutical |
| title | Fucoidan Extracted From Sporophyll of Undaria pinnatifida Grown in Weihai, China – Chemical Composition and Comparison of Antioxidant Activity of Different Molecular Weight Fractions |
| title_full | Fucoidan Extracted From Sporophyll of Undaria pinnatifida Grown in Weihai, China – Chemical Composition and Comparison of Antioxidant Activity of Different Molecular Weight Fractions |
| title_fullStr | Fucoidan Extracted From Sporophyll of Undaria pinnatifida Grown in Weihai, China – Chemical Composition and Comparison of Antioxidant Activity of Different Molecular Weight Fractions |
| title_full_unstemmed | Fucoidan Extracted From Sporophyll of Undaria pinnatifida Grown in Weihai, China – Chemical Composition and Comparison of Antioxidant Activity of Different Molecular Weight Fractions |
| title_short | Fucoidan Extracted From Sporophyll of Undaria pinnatifida Grown in Weihai, China – Chemical Composition and Comparison of Antioxidant Activity of Different Molecular Weight Fractions |
| title_sort | fucoidan extracted from sporophyll of undaria pinnatifida grown in weihai china chemical composition and comparison of antioxidant activity of different molecular weight fractions |
| topic | fucoidan molecular weight antioxidant fraction chemical composition nutraceutical |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2021.636930/full |
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