Nutritional assessment models for diabetes and aging
Abstract Diabetes is a chronic disease, and its complexity and its various complications complicate studies in diabetes management. Aging is one of the main risk factors for diabetes, and elderly are a high‐risk group for developing the disease. In recent years, increasing evidence has revealed the...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-12-01
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| Series: | Food Frontiers |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/fft2.168 |
| _version_ | 1811215556963991552 |
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| author | Yuxi Wen Yuanyuan Liu Qihui Huang Mohamed A. Farag Xiaoqing Li Xuzhi Wan Chao Zhao |
| author_facet | Yuxi Wen Yuanyuan Liu Qihui Huang Mohamed A. Farag Xiaoqing Li Xuzhi Wan Chao Zhao |
| author_sort | Yuxi Wen |
| collection | DOAJ |
| description | Abstract Diabetes is a chronic disease, and its complexity and its various complications complicate studies in diabetes management. Aging is one of the main risk factors for diabetes, and elderly are a high‐risk group for developing the disease. In recent years, increasing evidence has revealed the underlying molecular basis for aging diabetes and its connection to related signal pathways. Several key pathways in the aging process can affect insulin secretion and induce diabetes. In this review, we propose a possible connection between diabetes and aging in terms of development timeline and molecular pathology to better understand this interaction between two diseases, especially aging diabetes. Additionally, cell and animal models associated with diabetes are summarized, as well as a summary of models currently being used to study aging diabetes, and their strengths and limitations are also presented. The explanation of these types of models would help us to better understand the relationship between type 2 diabetes and aging and provide a basis for subsequent research on disease mechanisms and/or drug development. |
| first_indexed | 2024-04-12T06:24:30Z |
| format | Article |
| id | doaj.art-3909aaf302204c0a8139fa01d45bc134 |
| institution | Directory Open Access Journal |
| issn | 2643-8429 |
| language | English |
| last_indexed | 2024-04-12T06:24:30Z |
| publishDate | 2022-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Food Frontiers |
| spelling | doaj.art-3909aaf302204c0a8139fa01d45bc1342022-12-22T03:44:12ZengWileyFood Frontiers2643-84292022-12-013468970510.1002/fft2.168Nutritional assessment models for diabetes and agingYuxi Wen0Yuanyuan Liu1Qihui Huang2Mohamed A. Farag3Xiaoqing Li4Xuzhi Wan5Chao Zhao6College of Marine Sciences Fujian Agriculture and Forestry University Fuzhou ChinaCollege of Food Science Fujian Agriculture and Forestry University Fuzhou ChinaCollege of Marine Sciences Fujian Agriculture and Forestry University Fuzhou ChinaPharmacognosy Department, College of Pharmacy Cairo University Cairo EgyptSchool of Food Science and Engineering South China University of Technology Guangzhou ChinaCollege of Biosystem Engineering and Food Science Zhejiang University Hangzhou ChinaCollege of Marine Sciences Fujian Agriculture and Forestry University Fuzhou ChinaAbstract Diabetes is a chronic disease, and its complexity and its various complications complicate studies in diabetes management. Aging is one of the main risk factors for diabetes, and elderly are a high‐risk group for developing the disease. In recent years, increasing evidence has revealed the underlying molecular basis for aging diabetes and its connection to related signal pathways. Several key pathways in the aging process can affect insulin secretion and induce diabetes. In this review, we propose a possible connection between diabetes and aging in terms of development timeline and molecular pathology to better understand this interaction between two diseases, especially aging diabetes. Additionally, cell and animal models associated with diabetes are summarized, as well as a summary of models currently being used to study aging diabetes, and their strengths and limitations are also presented. The explanation of these types of models would help us to better understand the relationship between type 2 diabetes and aging and provide a basis for subsequent research on disease mechanisms and/or drug development.https://doi.org/10.1002/fft2.168aginganimal modelassessmentcell modeldiabetesfood nutrition |
| spellingShingle | Yuxi Wen Yuanyuan Liu Qihui Huang Mohamed A. Farag Xiaoqing Li Xuzhi Wan Chao Zhao Nutritional assessment models for diabetes and aging Food Frontiers aging animal model assessment cell model diabetes food nutrition |
| title | Nutritional assessment models for diabetes and aging |
| title_full | Nutritional assessment models for diabetes and aging |
| title_fullStr | Nutritional assessment models for diabetes and aging |
| title_full_unstemmed | Nutritional assessment models for diabetes and aging |
| title_short | Nutritional assessment models for diabetes and aging |
| title_sort | nutritional assessment models for diabetes and aging |
| topic | aging animal model assessment cell model diabetes food nutrition |
| url | https://doi.org/10.1002/fft2.168 |
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