Downregulation of the Protein C Signaling System Is Associated with COVID-19 Hypercoagulability—A Single-Cell Transcriptomics Analysis

Downregulation of the Protein C Signaling System Is Associated with COVID-19 Hypercoagulability—A Single-Cell Transcriptomics Analysis

Because of the interface between coagulation and the immune response, it is expected that COVID-19-associated coagulopathy occurs via activated protein C signaling. The objective was to explore putative changes in the expression of the protein C signaling network in the liver, peripheral blood monon...

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Bibliographic Details
Main Authors: Bruna Rafaela Santos Silva, Carlos Poblete Jara, Davi Sidarta-Oliveira, Licio A. Velloso, William H. Velander, Eliana P. Araújo
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Viruses
Subjects:
antigen-presenting cell
computational biology
blood coagulation disorders
endothelial cells
SARS-CoV-2
Online Access:https://www.mdpi.com/1999-4915/14/12/2753

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