Clinical and polysomnographic characteristics of REM-related obstructive sleep apnea patients
Introduction The clinical importance of obstructive sleep apnea (OPSA), which can be prevalent during rapid eye movement (REM) sleep, is unclear. This study aimed to explore possible differences between patients with REM-related OSA and non-REM-related OSA. Methods This retrospective study consiste...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Publishing
2024-02-01
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| Series: | Pneumon |
| Subjects: | |
| Online Access: | https://www.pneumon.org/Clinical-and-polysomnographic-characteristics-of-REM-related-nobstructive-sleep-apnea,178466,0,2.html |
| _version_ | 1797223780272046080 |
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| author | Catherine Tsouknida Kostas Archontogeorgis Evangelia Nena Konstantina Chadia Pantelis Nikolaidis Stavros Anevlavis Nicholas-Tiberio Economou Georgia Trakada Paschalis Steiropoulos |
| author_facet | Catherine Tsouknida Kostas Archontogeorgis Evangelia Nena Konstantina Chadia Pantelis Nikolaidis Stavros Anevlavis Nicholas-Tiberio Economou Georgia Trakada Paschalis Steiropoulos |
| author_sort | Catherine Tsouknida |
| collection | DOAJ |
| description | Introduction
The clinical importance of obstructive sleep apnea (OPSA),
which can be prevalent during rapid eye movement (REM) sleep, is unclear. This
study aimed to explore possible differences between patients with REM-related
OSA and non-REM-related OSA.
Methods
This retrospective study consisted of two groups of OSA patients,
matched in age, gender and body mass index, who were examined at a Greek
tertiary hospital; 147 patients with REM-related OSA were compared with 147
patients with non-REM-related OSA.
Results
Respiratory events occurred predominantly during REM sleep in
REM-related OSA patients (p<0.001) and during non-rapid eye movement
sleep (NREM) in the control group (p<0.001). The majority of REM-related
OSA patients had mild OSA, while the majority of the control group had
severe OSA. REM-related OSA patients had lower Arousal Index (p<0.001),
lower Oxygen Desaturation Index (p<0.001), lower percent of recording time,
spent at oxyhemoglobin saturation below 90% (p<0.001) and shorter mean
event duration (p<0.001). The average SatO 2 % and the minimum SatO 2 %
oxyhemoglobin saturation during sleep, were significantly higher, compared to
the control group (p=0.002 and p=0.005, respectively). When comparing the
anthropometric characteristics, the majority of the clinical features and the
reported comorbidities, no significant differences were found between the two
groups. However, REM-related OSA patients reported less frequently, excessive
daytime sleepiness (p<0.001). Also, a positive correlation was found between
reported insomnia and the minimum SatO 2 % in them.
Conclusions
Our results show that REM-related OSA patients, despite
their milder polysomnographic phenotype, they do not carry a lighter
comorbidity load, when compared to non-REM-related OSA patients. |
| first_indexed | 2024-04-24T13:42:40Z |
| format | Article |
| id | doaj.art-390e78f992474177ba9ad1d076532ab4 |
| institution | Directory Open Access Journal |
| issn | 1105-848X 1791-4914 |
| language | English |
| last_indexed | 2024-04-24T13:42:40Z |
| publishDate | 2024-02-01 |
| publisher | European Publishing |
| record_format | Article |
| series | Pneumon |
| spelling | doaj.art-390e78f992474177ba9ad1d076532ab42024-04-04T07:37:14ZengEuropean PublishingPneumon1105-848X1791-49142024-02-0137111110.18332/pne/178466178466Clinical and polysomnographic characteristics of REM-related obstructive sleep apnea patientsCatherine Tsouknida0Kostas Archontogeorgis1Evangelia Nena2Konstantina Chadia3https://orcid.org/0009-0008-7253-6943Pantelis Nikolaidis4Stavros Anevlavis5Nicholas-Tiberio Economou6Georgia Trakada7Paschalis Steiropoulos8https://orcid.org/0000-0001-7121-6253Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceProgram in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceLaboratory of Social Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceProgram in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceSchool of Health and Caring Sciences, University of West Attica, Athens, GreeceProgram in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceProgram in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceDepartment of Therapeutics, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, GreeceProgram in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, GreeceIntroduction The clinical importance of obstructive sleep apnea (OPSA), which can be prevalent during rapid eye movement (REM) sleep, is unclear. This study aimed to explore possible differences between patients with REM-related OSA and non-REM-related OSA. Methods This retrospective study consisted of two groups of OSA patients, matched in age, gender and body mass index, who were examined at a Greek tertiary hospital; 147 patients with REM-related OSA were compared with 147 patients with non-REM-related OSA. Results Respiratory events occurred predominantly during REM sleep in REM-related OSA patients (p<0.001) and during non-rapid eye movement sleep (NREM) in the control group (p<0.001). The majority of REM-related OSA patients had mild OSA, while the majority of the control group had severe OSA. REM-related OSA patients had lower Arousal Index (p<0.001), lower Oxygen Desaturation Index (p<0.001), lower percent of recording time, spent at oxyhemoglobin saturation below 90% (p<0.001) and shorter mean event duration (p<0.001). The average SatO 2 % and the minimum SatO 2 % oxyhemoglobin saturation during sleep, were significantly higher, compared to the control group (p=0.002 and p=0.005, respectively). When comparing the anthropometric characteristics, the majority of the clinical features and the reported comorbidities, no significant differences were found between the two groups. However, REM-related OSA patients reported less frequently, excessive daytime sleepiness (p<0.001). Also, a positive correlation was found between reported insomnia and the minimum SatO 2 % in them. Conclusions Our results show that REM-related OSA patients, despite their milder polysomnographic phenotype, they do not carry a lighter comorbidity load, when compared to non-REM-related OSA patients.https://www.pneumon.org/Clinical-and-polysomnographic-characteristics-of-REM-related-nobstructive-sleep-apnea,178466,0,2.htmlinsomniapolysomnographyobstructive sleep apneasleep disordered breathingrem-relatedosa |
| spellingShingle | Catherine Tsouknida Kostas Archontogeorgis Evangelia Nena Konstantina Chadia Pantelis Nikolaidis Stavros Anevlavis Nicholas-Tiberio Economou Georgia Trakada Paschalis Steiropoulos Clinical and polysomnographic characteristics of REM-related obstructive sleep apnea patients Pneumon insomnia polysomnography obstructive sleep apnea sleep disordered breathing rem-related osa |
| title | Clinical and polysomnographic characteristics of REM-related
obstructive sleep apnea patients |
| title_full | Clinical and polysomnographic characteristics of REM-related
obstructive sleep apnea patients |
| title_fullStr | Clinical and polysomnographic characteristics of REM-related
obstructive sleep apnea patients |
| title_full_unstemmed | Clinical and polysomnographic characteristics of REM-related
obstructive sleep apnea patients |
| title_short | Clinical and polysomnographic characteristics of REM-related
obstructive sleep apnea patients |
| title_sort | clinical and polysomnographic characteristics of rem related obstructive sleep apnea patients |
| topic | insomnia polysomnography obstructive sleep apnea sleep disordered breathing rem-related osa |
| url | https://www.pneumon.org/Clinical-and-polysomnographic-characteristics-of-REM-related-nobstructive-sleep-apnea,178466,0,2.html |
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