Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs
To understand the progression of porcine epidemic diarrhea virus infection, we inoculated gnotobiotic pigs with a newly emerged US strain, PC21A, of the virus. At 24–48 hours postinoculation, the pigs exhibited severe diarrhea and vomiting, fecal shedding, viremia, and severe atrophic enteritis. The...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2014-04-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/20/4/13-1685_article |
| _version_ | 1828432570708131840 |
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| author | Kwonil Jung Qiuhong Wang Kelly A. Scheuer Zhongyan Lu Yan Zhang Linda J. Saif |
| author_facet | Kwonil Jung Qiuhong Wang Kelly A. Scheuer Zhongyan Lu Yan Zhang Linda J. Saif |
| author_sort | Kwonil Jung |
| collection | DOAJ |
| description | To understand the progression of porcine epidemic diarrhea virus infection, we inoculated gnotobiotic pigs with a newly emerged US strain, PC21A, of the virus. At 24–48 hours postinoculation, the pigs exhibited severe diarrhea and vomiting, fecal shedding, viremia, and severe atrophic enteritis. These findings confirm that strain PC21A is highly enteropathogenic. |
| first_indexed | 2024-12-10T18:22:14Z |
| format | Article |
| id | doaj.art-390f71675d97487aadd4072376a36dc7 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-10T18:22:14Z |
| publishDate | 2014-04-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-390f71675d97487aadd4072376a36dc72022-12-22T01:38:10ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592014-04-0120466867110.3201/eid2004.131685Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic PigsKwonil JungQiuhong WangKelly A. ScheuerZhongyan LuYan ZhangLinda J. SaifTo understand the progression of porcine epidemic diarrhea virus infection, we inoculated gnotobiotic pigs with a newly emerged US strain, PC21A, of the virus. At 24–48 hours postinoculation, the pigs exhibited severe diarrhea and vomiting, fecal shedding, viremia, and severe atrophic enteritis. These findings confirm that strain PC21A is highly enteropathogenic.https://wwwnc.cdc.gov/eid/article/20/4/13-1685_articleporcine epidemic diarrhea virusporcine epidemic diarrhea, pathogenesis, outbreak, USA, gnotobiotic pigs, US strain, pigs, strain PC21A, viruses, enteropathogenic |
| spellingShingle | Kwonil Jung Qiuhong Wang Kelly A. Scheuer Zhongyan Lu Yan Zhang Linda J. Saif Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs Emerging Infectious Diseases porcine epidemic diarrhea virus porcine epidemic diarrhea, pathogenesis, outbreak, USA, gnotobiotic pigs, US strain, pigs, strain PC21A, viruses, enteropathogenic |
| title | Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs |
| title_full | Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs |
| title_fullStr | Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs |
| title_full_unstemmed | Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs |
| title_short | Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs |
| title_sort | pathology of us porcine epidemic diarrhea virus strain pc21a in gnotobiotic pigs |
| topic | porcine epidemic diarrhea virus porcine epidemic diarrhea, pathogenesis, outbreak, USA, gnotobiotic pigs, US strain, pigs, strain PC21A, viruses, enteropathogenic |
| url | https://wwwnc.cdc.gov/eid/article/20/4/13-1685_article |
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