Interactions of marine sulfated glycans with antithrombin and platelet factor 4
The molecular interactions of sulfated glycans, such as heparin, with antithrombin (AT) and platelet factor 4 (PF4) are essential for certain biological events such as anticoagulation and heparin induced thrombocytopenia (HIT). In this study, a library including 84 sulfated glycans (polymers and oli...
Main Authors: | Wenjing Zhang, Weihua Jin, Vitor H. Pomin, Fuming Zhang, Robert J. Linhardt |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
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Series: | Frontiers in Molecular Biosciences |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.954752/full |
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