Keap1/Nrf2 Signaling Pathway
Nuclear factor, erythroid 2-like transcription factor 2 (Nrf2) and its cytoplasmic inhibitor, kelch-like ECH-associated protein 1 (Keap1), comprise a redox-responsive endogenous antioxidant defense module that orchestrates the expression of cytoprotective genes to maintain homeostasis [...]
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/10/6/828 |
| _version_ | 1797533052856958976 |
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| author | Gerasimos P. Sykiotis |
| author_facet | Gerasimos P. Sykiotis |
| author_sort | Gerasimos P. Sykiotis |
| collection | DOAJ |
| description | Nuclear factor, erythroid 2-like transcription factor 2 (Nrf2) and its cytoplasmic inhibitor, kelch-like ECH-associated protein 1 (Keap1), comprise a redox-responsive endogenous antioxidant defense module that orchestrates the expression of cytoprotective genes to maintain homeostasis [...] |
| first_indexed | 2024-03-10T11:09:09Z |
| format | Article |
| id | doaj.art-3913e0bcec83498992053ee3f3837b94 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-10T11:09:09Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-3913e0bcec83498992053ee3f3837b942023-11-21T20:54:57ZengMDPI AGAntioxidants2076-39212021-05-0110682810.3390/antiox10060828Keap1/Nrf2 Signaling PathwayGerasimos P. Sykiotis0Service of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital, 1011 Lausanne, SwitzerlandNuclear factor, erythroid 2-like transcription factor 2 (Nrf2) and its cytoplasmic inhibitor, kelch-like ECH-associated protein 1 (Keap1), comprise a redox-responsive endogenous antioxidant defense module that orchestrates the expression of cytoprotective genes to maintain homeostasis [...]https://www.mdpi.com/2076-3921/10/6/828n/a |
| spellingShingle | Gerasimos P. Sykiotis Keap1/Nrf2 Signaling Pathway Antioxidants n/a |
| title | Keap1/Nrf2 Signaling Pathway |
| title_full | Keap1/Nrf2 Signaling Pathway |
| title_fullStr | Keap1/Nrf2 Signaling Pathway |
| title_full_unstemmed | Keap1/Nrf2 Signaling Pathway |
| title_short | Keap1/Nrf2 Signaling Pathway |
| title_sort | keap1 nrf2 signaling pathway |
| topic | n/a |
| url | https://www.mdpi.com/2076-3921/10/6/828 |
| work_keys_str_mv | AT gerasimospsykiotis keap1nrf2signalingpathway |